Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | STAT3 | P40763 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9004549 | 0.77 | STAT3 (0.33) | ALOX15TSHRPTPN1STAT3 | |
| SCHEMBL23863717 | 0.76 | ALDH1A1 (0.42) | TSHR | |
| SCHEMBL11235250 | 0.70 | PTPN1 (0.30) | PTPN1STAT3 | |
| SCHEMBL24535254 | 0.70 | PTPN1 (0.30) | PTPN1STAT3 | |
| SCHEMBL3380118 | 0.69 | HMGCR (0.50) | TSHR | |
| SCHEMBL28568122 | 0.68 | PTPN1 (0.46) | ALOX15TSHRPTPN1STAT3 | |
| SCHEMBL13318696 | 0.67 | STAT3 (0.33) | STAT3 | |
| SCHEMBL4669160 | 0.67 | KDM4E (0.31) | ALOX15 | |
| SCHEMBL13039627 | 0.65 | ALDH1A1 (0.39) | TSHRPTPN1STAT3 | |
| SCHEMBL3098861 | 0.64 | STAT3 (0.34) | ALOX15TSHRSTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8497376-B2 | 4-Cyano-1H-imidazole-2-carboxylic acid [2-cyclohex-1-enyl-4-(2,6-dioxo-piperidin-4-yl)-phenyl]-amide; tyrosine kinase inhibitor; autoimmune diseases, antiinflammatory, anticarcinogenic agent | JANSSEN PHARMACEUTICA N.V. (BE) | 2013-07-30 | — | — | US | disclosed |
| US-20090105296-A1 | INHIBITORS OF C-FMS KINASE | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105296-A1 | INHIBITORS OF C-FMS KINASE | MUSK, FRK, FES | ALOX15 3558/4885TSHR 1277/4885PTPN1 391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.