Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 17/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1387823 | 0.89 | CCKBR (0.70) | CCKBR | |
| SCHEMBL8540475 | 0.88 | CCKBR (0.51) | CCKBR | |
| SCHEMBL7754058 | 0.86 | CCKAR (0.74) | CCKBR | |
| SCHEMBL8635376 | 0.83 | CCKBR (1.00) | CCKBR | |
| SCHEMBL9573642 | 0.82 | CCKBR (0.62) | CCKBR | |
| SCHEMBL8547385 | 0.78 | CCKBR (0.70) | CCKBR | |
| SCHEMBL8634884 | 0.76 | CCKBR (0.93) | CCKBR | |
| SCHEMBL8638925 | 0.76 | CCKBR (1.00) | CCKBR | |
| SCHEMBL8634816 | 0.76 | CCKBR (1.00) | CCKBR | |
| SCHEMBL8639233 | 0.76 | CCKBR (1.00) | CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0698014-B1 | 3-PHENYLUREIDO-1,5-BENZODIAZEPINE-DIONES USEFUL AS GASTRIN OR CCK ANTAGONISTS | GLAXO WELLCOME SPA (IT) | 1998-07-22 | — | — | EP | claimed |
| JP-H08509236-A | — | — | 1996-10-01 | — | — | JP | claimed |
| EP-0698014-A1 | 3-PHENYLUREIDO-1,5-BENZODIAZEPINE-DIONES USEFUL AS GASTRIN OR CCK ANTAGONISTS | GLAXO S.p.A. (IT) | 1996-02-28 | — | — | EP | claimed |
| WO-1994025444-A1 | 3-PHENYLUREIDO-1,5-BENZODIAZEPINE-DIONES USEFUL AS GASTRIN OR CCK ANTAGONISTS | GLAXO SPA (IT) | 1994-11-10 | — | — | WO | claimed |
| EP-0698014-B1 | 3-PHENYLUREIDO-1,5-BENZODIAZEPINE-DIONES USEFUL AS GASTRIN OR CCK ANTAGONISTS | GLAXO WELLCOME SPA (IT) | 1998-07-22 | — | — | EP | disclosed |
| US-5641775-A | 3-phenylureido-1,5-benzodiazepine-diones useful as gastrin or antagonists | GLAXO SPA (IT) | 1997-06-24 | — | — | US | disclosed |
| EP-0698014-A1 | 3-PHENYLUREIDO-1,5-BENZODIAZEPINE-DIONES USEFUL AS GASTRIN OR CCK ANTAGONISTS | GLAXO S.p.A. (IT) | 1996-02-28 | — | — | EP | disclosed |
| WO-1994025444-A1 | 3-PHENYLUREIDO-1,5-BENZODIAZEPINE-DIONES USEFUL AS GASTRIN OR CCK ANTAGONISTS | GLAXO SPA (IT) | 1994-11-10 | — | — | WO | disclosed |