Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 8/20 | 0.42 |
| ▸ | CTSL | P07711 | 5/20 | 0.41 |
| ▸ | CTSB | P07858 | 5/20 | 0.41 |
| ▸ | CTSH | P09668 | 4/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | REN | P00797 | 2/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13235676 | 1.00 | CTSK (0.42) | CTSKCTSLCTSBCTSHLTA4H | |
| SCHEMBL13954308 | 1.00 | CTSK (0.42) | CTSKCTSLCTSBCTSHLTA4H | |
| SCHEMBL13971373 | 1.00 | CTSK (0.42) | CTSKCTSLCTSBCTSHLTA4H | |
| SCHEMBL24919466 | 0.88 | CTSK (0.36) | CTSKCTSLCTSBCTSHLTA4H | |
| SCHEMBL7794348 | 0.83 | LTA4H (0.46) | CTSKCTSLCTSBLTA4H | |
| SCHEMBL5326239 | 0.83 | LTA4H (0.46) | CTSKCTSLCTSBLTA4H | |
| SCHEMBL28948946 | 0.83 | LTA4H (0.46) | CTSKCTSLCTSBLTA4H | |
| SCHEMBL14947101 | 0.83 | LTA4H (0.46) | CTSKCTSLCTSBLTA4H | |
| SCHEMBL19817250 | 0.83 | LTA4H (0.46) | CTSKCTSLCTSBLTA4H | |
| SCHEMBL9099 | 0.81 | EPHX1 (0.49) | CTSKCTSLCTSBREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024059472-A1 | MACROCYCLIC IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-03-21 | — | — | WO | disclosed |
| WO-2023225661-A1 | MACROCYCLIC IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-11-23 | — | — | WO | disclosed |
| WO-2023102507-A1 | MACROCYCLIC IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-06-08 | — | — | WO | disclosed |
| WO-2023004240-A1 | MACROCYLIC IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-01-26 | — | — | WO | disclosed |
| WO-2023288213-A1 | MACROCYCLIC IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-01-19 | — | — | WO | disclosed |
| WO-2020227365-A1 | INHIBITING USP19 | INTEGRAL EARLY DISCOVERY, INC. (US) | 2020-11-12 | — | — | WO | disclosed |
| EP-1250353-B1 | P21 DERIVED PEPTIDES CAPABLE OF INHIBITING CDK/CYCLIN COMPLEXES | CYCLACEL LTD (GB) | 2009-04-08 | — | — | EP | disclosed |