Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 5/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19817250 | 1.00 | LTA4H (0.46) | LTA4HCTSKSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL5326239 | 1.00 | LTA4H (0.46) | LTA4HCTSKSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7794348 | 1.00 | LTA4H (0.46) | LTA4HCTSKSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL28948946 | 1.00 | LTA4H (0.46) | LTA4HCTSKSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL18050391 | 0.98 | LTA4H (0.44) | LTA4HCTSKSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL17276053 | 0.98 | LTA4H (0.44) | LTA4HCTSKSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL13285738 | 0.98 | LTA4H (0.44) | LTA4HCTSKSLC1A3SLC1A2SLC1A1 | |
| Hydrochloric Acid SCHEMBL16054796 | 0.96 | LTA4H (0.43) | LTA4HCTSKSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL10138774 | 0.93 | LTA4H (0.41) | LTA4HSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL13005942 | 0.93 | LTA4H (0.41) | LTA4HSLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240024410-A1 | THREE-DIMENTIONAL SURFACE FOR PROTEIN AND SMALL MOLECULE MICROARRAYS | THE JOHNS HOPKINS UNIVERSITY | 2024-01-25 | — | — | US | disclosed |
| US-20230322668-A1 | PROTEASE INHIBITORS AS ANTIVIRALS | ACEA Therapeutics, Inc. (US) | 2023-10-12 | — | — | US | disclosed |
| US-11753373-B2 | Protease inhibitors as antivirals | ACEA Therapeutics, Inc. (US) | 2023-09-12 | — | — | US | disclosed |
| US-11708391-B2 | Rapaglutins, novel inhibitors of GLUT and use thereof | THE JOHNS HOPKINS UNIVERSITY (US) | 2023-07-25 | — | — | US | disclosed |
| WO-2022224035-A2 | ANTI-GM1 ANTIBODY BINDING COMPOUNDS | POLYNEURON PHARMACEUTICALS AG (CH) | 2022-10-27 | — | — | WO | disclosed |
| US-20160368946-A1 | TRIPEPTIDE EPOXY KETONE PROTEASE INHIBITORS | ONYX THERAPEUTICS, INC. | 2016-12-22 | — | — | US | disclosed |
| US-9434761-B2 | Tripeptide epoxy ketone protease inhibitors | ONYX THERAPEUTICS, INC. (US) | 2016-09-06 | — | — | US | disclosed |
| US-9150899-B2 | Identification of compounds modifying a cellular response | 2CUREX (DK) | 2015-10-06 | — | — | US | disclosed |
| US-20130123140-A1 | IDENTIFICATION OF COMPOUNDS MODIFYING A CELLULAR RESPONSE | 2CUREX (DK) | 2013-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11708391-B2 | Rapaglutins, novel inhibitors of GLUT and use thereof | SLC2A1, SLC2A4, SLC2A2 | LTA4H 4135/4885CTSK 4463/4885SLC1A3 88/4885 |
| US-20240024410-A1 | THREE-DIMENTIONAL SURFACE FOR PROTEIN AND SMALL MOLECULE MICROARRAYS | MRPS23, CD2BP2, MRPL21 | LTA4H 4393/4885CTSK 4135/4885SLC1A3 3511/4885 |
| US-20160368946-A1 | TRIPEPTIDE EPOXY KETONE PROTEASE INHIBITORS | PREP, CTRL, ENPEP | LTA4H 271/4885CTSK 48/4885SLC1A3 2348/4885 |
| US-11753373-B2 | Protease inhibitors as antivirals | ACE, ACE2, TMPRSS15 | LTA4H 556/4885CTSK 86/4885SLC1A3 4017/4885 |
| US-20230322668-A1 | PROTEASE INHIBITORS AS ANTIVIRALS | ACE, ACE2, TMPRSS15 | LTA4H 556/4885CTSK 86/4885SLC1A3 4017/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.