⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28417634 | 0.97 | — | — | |
| SCHEMBL1369210 | 0.78 | ALDH1A1 (0.50) | — | |
| SCHEMBL15948328 | 0.74 | — | — | |
| SCHEMBL454310 | 0.74 | — | — | |
| SCHEMBL643261 | 0.74 | — | — | |
| SCHEMBL11591509 | 0.74 | — | — | |
| SCHEMBL84740 | 0.74 | — | — | |
| SCHEMBL2839473 | 0.74 | — | — | |
| SCHEMBL14281292 | 0.74 | — | — | |
| SCHEMBL2807100 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021061643-A1 | METHODS AND COMPOUNDS FOR RESTORING MUTANT p53 FUNCTION | PMV PHARMACEUTICALS, INC. (US) | 2021-04-01 | — | — | WO | disclosed |
| US-20180108492-A1 | PHOTOELECTRIC CONVERSION ELEMENT, SOLAR CELL, AND COMPOSITION | FUJIFILM CORPORATION (JP) | 2018-04-19 | — | — | US | disclosed |
| WO-2017049245-A2 | COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS | MODERNATX, INC. (US) | 2017-03-23 | — | — | WO | disclosed |
| WO-2014047024-A1 | IAP ANTAGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2014-03-27 | — | — | WO | disclosed |
| EP-1786792-B1 | THIAZOLE DERIVATIVES HAVING VAP-1 INHIBITORY ACTIVITY | ASTELLAS PHARMA INC (JP) | 2009-04-08 | — | — | EP | disclosed |