SCHEMBL454310

SCHEMBL454310

NNc1nccs1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6341016 0.97
Hydrochloric Acid SCHEMBL10762226 0.97
SCHEMBL1369210 0.78 ALDH1A1 (0.50)
Tert-Butyl Formate SCHEMBL28305753 0.77 TDP1 (0.41)
SCHEMBL643261 0.74
SCHEMBL2839473 0.74
SCHEMBL2807100 0.74
SCHEMBL13879142 0.74
SCHEMBL15948328 0.74
SCHEMBL14281292 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 271 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3976605-B1 METHODS FOR MAKING THIAZOLYLPYRAZOLE CARBOXYLIC ACIDS AND INTERMEDIATES THEREFOR BANTAM PHARMACEUTICAL LLC (US) 2025-08-20 EP claimed
US-12358905-B2 Methods for making thiazolypyrazole carboxylic acids and intermediates therefor Bantam Pharamceutical, LLC (US) 2025-07-15 US claimed
CN-116856183-A Method for manufacturing antibacterial and antiviral synthetic leather 苏州丰欣新材料科技有限公司 2023-10-10 CN claimed
US-20220267314-A1 METHODS FOR MAKING THIAZOLYPYRAZOLE CARBOXYLIC ACIDS AND INTERMEDIATES THEREFOR BANTAM PHARMACEUTICAL, LLC 2022-08-25 US claimed
CN-114867724-A Process for preparing thiazolyl pyrazolecarboxylic acids and intermediates thereof 班塔姆制药有限责任公司 2022-08-05 CN claimed
CN-113999187-A Thiazole hydrazone derivative and preparation method and application thereof 江西农业大学 2022-02-01 CN claimed
CN-111518630-A Laundry detergent with antibacterial function and preparation method thereof 杭州炫墨生物科技有限公司 2020-08-11 CN claimed
CN-108264488-A A kind of preparation method for replacing phthalazone class compound 天津瑞岭化工有限公司 2018-07-10 CN claimed
CN-1406122-A Topical cosmetic agents containing 2-hydrazino-1,3-heteroazoles HAARMANN & REIMER GMBH (DE) 2003-03-26 CN claimed
US-20020128268-A1 Use of 2-hydrazino-1,3-thiazoles as antioxidants HAARMANN & REIMER GMBH (DE) 2002-09-12 US claimed
WO-2002034265-A1 USE OF 2-HYDRAZINO-1,3-THIAZOLES AS ANTIOXIDANTS HAARMANN & REIMER GMBH (DE) 2002-05-02 WO claimed
EP-0110298-B1 ACRIDANONE DERIVATIVES F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1988-06-01 EP claimed
US-4711889-A Schistosomicidal acridanone hydrazones HOFFMAN-LA ROCHE INC. (US) 1987-12-08 US claimed
EP-0111205-B1 ACRIDANONE DERIVATIVES F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1987-04-01 EP claimed
US-4544659-A PARASITICIDES HOFFMAN-LA ROCHE INC. (US) 1985-10-01 US claimed
US-4101658-A Antibacterial hydrazono cephalosporins SHIONOGI & CO., LTD. (JP) 1978-07-18 US claimed
JP-4321685-A None JP disclosed
JP-4288076-A None JP disclosed
US-3987234-A ACRYLIC ESTER POLYMERS HENKEL & CIE G.M.B.H. (DT) 1976-10-19 US disclosed
US-3936444-A FROM A LACTIM-ETHER AND AN ARYL OR HETEROARYL HYDRAZINE, ACID CATALYST BAYER AKTIENGESELLSCHAFT (DT) 1976-02-03 US disclosed