SCHEMBL13879290

SCHEMBL13879290

CC(C)CCCCNCC(C)C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.43
HRH4 Q9H3N8 2/20 0.42
HRH3 Q9Y5N1 2/20 0.42
ADH1B P00325 1/20 0.35
ADH1C P00326 1/20 0.35
ADH1A P07327 1/20 0.35
PKM P14618 1/20 0.34
CA2 P00918 1/20 0.34
ALDH1A1 P00352 2/20 0.33
CYP1A2 P05177 2/20 0.33
CYP2C19 P33261 2/20 0.33
TSHR P16473 1/20 0.33
EPHX1 P07099 1/20 0.32
GRIN1 Q05586 2/20 0.31
GRIN2A Q12879 2/20 0.31
ANPEP P15144 2/20 0.31
ERAP2 Q6P179 1/20 0.31
SCN1A P35498 1/20 0.30
SCN2A Q99250 1/20 0.30
SCN3A Q9NY46 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21106835 0.97 HRH4 (0.43) LMNAHRH4HRH3ADH1BADH1C
SCHEMBL22861967 0.97 HRH4 (0.43) LMNAHRH4HRH3ADH1BADH1C
SCHEMBL9193203 0.97 HRH4 (0.43) LMNAHRH4HRH3ADH1BADH1C
SCHEMBL23806605 0.97 HRH4 (0.43) LMNAHRH4HRH3ADH1BADH1C
SCHEMBL11207707 0.97 HRH4 (0.43) LMNAHRH4HRH3ADH1BADH1C
SCHEMBL23695755 0.97 HRH4 (0.43) LMNAHRH4HRH3ADH1BADH1C
SCHEMBL22856504 0.97 HRH4 (0.43) LMNAHRH4HRH3ADH1BADH1C
SCHEMBL13879291 0.92 LMNA (0.39) LMNAHRH4HRH3ADH1BADH1C
SCHEMBL9624660 0.89 HRH4 (0.47) HRH4HRH3ADH1BADH1CADH1A
SCHEMBL21106926 0.87 HRH4 (0.36) LMNAHRH4HRH3SCN1ASCN2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240025878-A1 MDM2 DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS, INC. 2024-01-25 US disclosed
US-20240025878-A1 MDM2 DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS, INC. 2024-01-25 US disclosed
US-20230234953-A1 IRAK DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS, INC. 2023-07-27 US disclosed
EP-4194457-A1 COMPOUND FOR TARGETING AND DEGRADING PROTEIN, AND PREPARATION METHOD THEREFOR AND USE THEREOF Shanghai Leadingtac Pharmaceutical Co., Ltd. (CN) 2023-06-14 EP disclosed
US-20230150974-A1 COMPOUNDS AND USES THEREOF FOGHORN THERAPEUTICS INC. 2023-05-18 US disclosed
US-10428070-B2 Hepatitis B antiviral agents ENANTA PHARMACEUTICALS, INC. (US) 2019-10-01 US disclosed
US-20190177320-A1 HEPATITIS B ANTIVIRAL AGENTS ENANTA PHARMACEUTICALS, INC. 2019-06-13 US disclosed
US-20190151403-A1 NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF S&T GLOBAL INC. 2019-05-23 US disclosed
US-9365599-B2 N3S1 chelator-folate derivatives, preparation method thereof and composition for diagnosis or treatment of cancer containing the same as an active ingredient KOREA ATOMIC ENERGY RESEARCH INSTITUTE (KR) 2016-06-14 US disclosed
US-20130210887-A1 DENDRIMERS AS NON-VIRAL VEHICLES FOR GENE THERAPY UNIVERSIDAD DE CASTILLA LA MANCHA (ES) 2013-08-15 US disclosed
US-20090111805-A1 BICYCLIC HETEROAROMATIC DERIVATIVES USEFUL AS ANTICANCER AGENTS PFIZER INC. 2009-04-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240025878-A1 MDM2 DEGRADERS AND USES THEREOF MDM2, TP53, MDM4 LMNA 2219/4885HRH4 4261/4885HRH3 4228/4885
US-20230234953-A1 IRAK DEGRADERS AND USES THEREOF IRAK2, IRAK3, IRAK1 LMNA 1656/4885HRH4 3886/4885HRH3 3631/4885
US-20090111805-A1 BICYCLIC HETEROAROMATIC DERIVATIVES USEFUL AS ANTICANCER AGENTS CCNB1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CCNY LMNA 1304/4885HRH4 503/4885HRH3 832/4885
US-20130210887-A1 DENDRIMERS AS NON-VIRAL VEHICLES FOR GENE THERAPY HAVCR2, GMFG, CD74 LMNA 2611/4885HRH4 4341/4885HRH3 4372/4885
US-20230150974-A1 COMPOUNDS AND USES THEREOF VHL, CLN6, TFEB LMNA 225/4885HRH4 3580/4885HRH3 3347/4885
US-20190151403-A1 NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF MALT1, MYLK2, FKBP1B LMNA 3053/4885HRH4 4739/4885HRH3 4818/4885
US-20190177320-A1 HEPATITIS B ANTIVIRAL AGENTS HAVCR2, SLC10A1, HDGF LMNA 2852/4885HRH4 2991/4885HRH3 3243/4885
US-10428070-B2 Hepatitis B antiviral agents HAVCR2, SLC10A1, HDGF LMNA 2852/4885HRH4 2991/4885HRH3 3243/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.