Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 1/20 | 0.46 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.46 |
| ▸ | ITGAL | P20701 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 4/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13879387 | 0.87 | ELANE (0.59) | ITGB2ICAM1ITGALELANEALDH1A1 | |
| SCHEMBL13879388 | 0.86 | ALDH1A1 (0.53) | ITGB2ICAM1ITGALELANEAR | |
| SCHEMBL13879396 | 0.78 | ITGAL (0.73) | ITGB2ICAM1ITGALELANE | |
| SCHEMBL30385466 | 0.78 | ELANE (0.56) | ITGB2ICAM1ITGALELANEAR | |
| SCHEMBL13879382 | 0.77 | L3MBTL1 (0.45) | ITGB2ICAM1ITGALELANEOPRM1 | |
| SCHEMBL13879386 | 0.73 | ITGB2 (0.43) | ITGB2ICAM1ITGALELANEAR | |
| SCHEMBL8295620 | 0.72 | ALDH1A1 (0.74) | ITGB2ICAM1ITGALELANEOPRM1 | |
| Hydrochloric Acid SCHEMBL30385756 | 0.72 | AR (0.60) | ELANEARALDH1A1TAS2R8HTT | |
| Hydrochloric Acid SCHEMBL8295931 | 0.71 | MAPK1 (0.73) | ITGB2ICAM1ITGALELANEOPRM1 | |
| SCHEMBL13879391 | 0.70 | LMNA (0.43) | ITGB2ICAM1ITGALELANEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090099186-A1 | INHIBITORS OF VIRAL REPLICATION | INTERMUNE, INC. | 2009-04-16 | — | — | US | disclosed |
| US-20090099186-A1 | INHIBITORS OF VIRAL REPLICATION | INTERMUNE, INC. | 2009-04-16 | — | — | US | disclosed |
| WO-2007047146-A2 | INHIBITORS OF VIRAL REPLICATION | INTERMUNE, INC. (US) | 2007-04-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090099186-A1 | INHIBITORS OF VIRAL REPLICATION | EIF2AK2, HAVCR2, RTF2 | ITGB2 4487/4885ICAM1 2947/4885ITGAL 4495/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.