Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC4 | O15439 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 6/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 6/20 | 0.43 |
| ▸ | PPARD | Q03181 | 6/20 | 0.43 |
| ▸ | PPARA | Q07869 | 6/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TLR2 | O60603 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | FABP4 | P15090 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7866499 | 1.00 | ABCC4 (0.54) | ABCC4MAPTTSHRLMNANFKB1 | |
| SCHEMBL21297377 | 1.00 | ABCC4 (0.54) | ABCC4MAPTTSHRLMNANFKB1 | |
| SCHEMBL29158015 | 0.91 | TSHR (0.50) | ABCC4MAPTTSHRLMNANFKB1 | |
| SCHEMBL223005 | 0.84 | PHF8 (0.50) | ABCC4MAPTTSHRLMNANFKB1 | |
| SCHEMBL7974734 | 0.83 | GPR84 (0.44) | ABCC4MAPTTSHRLMNAGPR84 | |
| SCHEMBL3739008 | 0.81 | FAAH (0.61) | TSHRGPR84FFAR1FFAR4PPARG | |
| SCHEMBL1961182 | 0.81 | FAAH (0.61) | TSHRGPR84FFAR1FFAR4PPARG | |
| SCHEMBL2943507 | 0.81 | FAAH (0.61) | TSHRGPR84FFAR1FFAR4PPARG | |
| SCHEMBL3741727 | 0.81 | ALDH1A1 (0.66) | ABCC4MAPTTSHRLMNASMN1; SMN2 | |
| SCHEMBL2939525 | 0.81 | FAAH (0.61) | TSHRGPR84FFAR1FFAR4PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1699497-B1 | ANTIMICROBIAL CONTACT LENSES AND METHODS FOR THEIR PRODUCTION | JOHNSON & JOHNSON VISION CARE (US) | 2009-04-15 | — | — | EP | disclosed |