Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | PARP1 | P09874 | 2/20 | 0.31 |
| ▸ | TYMP | P19971 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1388040 | 0.77 | RAB9A (0.31) | ALDH1A1KDM4EHPGDHSD17B10PDE3B | |
| SCHEMBL694447 | 0.71 | MAPT (0.41) | ALDH1A1KDM4EHPGDKMT2ASMN1; SMN2 | |
| SCHEMBL557903 | 0.65 | ALDH1A1 (0.67) | ALDH1A1KDM4EHPGDKMT2ASMN1; SMN2 | |
| SCHEMBL166213 | 0.64 | ALDH1A1 (0.39) | ALDH1A1HSD17B10 | |
| SCHEMBL25590 | 0.63 | ALDH1A1 (0.61) | ALDH1A1KDM4EHPGDKMT2ASMN1; SMN2 | |
| SCHEMBL693173 | 0.63 | GAA (0.66) | KDM4EKMT2ASMN1; SMN2GAAMAPT | |
| SCHEMBL1451100 | 0.62 | TNKS2 (0.56) | ALDH1A1KDM4EHPGDSMN1; SMN2GAA | |
| SCHEMBL6587779 | 0.62 | F2 (0.51) | SMN1; SMN2DAOADORA1PARP1 | |
| SCHEMBL5794341 | 0.61 | IMPDH2 (0.43) | ALDH1A1KDM4EHPGDKMT2AGAA | |
| SCHEMBL3346300 | 0.61 | KDM4E (0.53) | ALDH1A1KDM4EHPGDKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-H08509967-A | — | — | 1996-10-22 | — | — | JP | claimed |
| EP-0690847-A1 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1996-01-10 | — | — | EP | claimed |
| WO-1994022835-A2 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1994-10-13 | — | — | WO | claimed |