Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 3/20 | 0.68 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.68 |
| ▸ | ITGAL | P20701 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | PYGL | P06737 | 7/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4280119 | 0.81 | ALDH1A1 (0.58) | ITGB2ICAM1ITGALALDH1A1ALOX15 | |
| SCHEMBL4280125 | 0.81 | ALDH1A1 (0.58) | ITGB2ICAM1ITGALALDH1A1ALOX15 | |
| SCHEMBL13879640 | 0.79 | PYGL (0.62) | ITGB2ICAM1ITGALALDH1A1PYGL | |
| SCHEMBL10858272 | 0.78 | ALDH1A1 (0.79) | ITGB2ICAM1ITGALALDH1A1LMNA | |
| SCHEMBL10858265 | 0.78 | ALDH1A1 (0.79) | ITGB2ICAM1ITGALALDH1A1LMNA | |
| SCHEMBL10824310 | 0.74 | ALDH1A1 (0.62) | ITGB2ICAM1ITGALALDH1A1 | |
| SCHEMBL13879639 | 0.73 | KDM4E (0.64) | ALDH1A1PYGLLMNA | |
| SCHEMBL7868578 | 0.72 | ALDH1A1 (0.67) | ITGB2ICAM1ITGALALDH1A1LMNA | |
| SCHEMBL7877285 | 0.72 | ALDH1A1 (0.67) | ITGB2ICAM1ITGALALDH1A1LMNA | |
| SCHEMBL6139179 | 0.71 | ALDH1A1 (0.61) | ITGB2ICAM1ITGALALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090099186-A1 | INHIBITORS OF VIRAL REPLICATION | INTERMUNE, INC. | 2009-04-16 | — | — | US | disclosed |
| US-20090099186-A1 | INHIBITORS OF VIRAL REPLICATION | INTERMUNE, INC. | 2009-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090099186-A1 | INHIBITORS OF VIRAL REPLICATION | EIF2AK2, HAVCR2, RTF2 | ITGB2 4487/4885ICAM1 2947/4885ITGAL 4495/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.