Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.39 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.39 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24921224 | 0.89 | MEN1 (0.60) | APPTP53MAPTHPGDTSHR | |
| SCHEMBL16560312 | 0.86 | XDH (0.49) | TDP1KDM1APDK1GRM5LMNA | |
| SCHEMBL2665020 | 0.82 | PARP15 (0.55) | TDP1KDM1APARP15PARP10PARP2 | |
| SCHEMBL8930160 | 0.82 | PARP15 (0.55) | TDP1KDM1APARP15PARP10PARP2 | |
| SCHEMBL13452225 | 0.81 | ACACB (0.47) | HPGDALDH1A1CYP1A2TDP1KDM1A | |
| SCHEMBL15301046 | 0.81 | TSHR (0.41) | APPTP53MAPTHPGDTSHR | |
| SCHEMBL21051452 | 0.81 | PARP15 (0.42) | APPTP53MAPTHPGDTSHR | |
| SCHEMBL23266127 | 0.80 | TP53 (0.54) | APPTP53MAPTHPGDTSHR | |
| SCHEMBL5481920 | 0.80 | TDP1 (0.62) | TP53TSHRALDH1A1MEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL28413630 | 0.80 | PARP15 (0.53) | TDP1KDM1APARP15PARP10PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2050734-A1 | PENTADIENAMIDE DERIVATIVE | Kyowa Hakko Kirin Co., Ltd. (JP) | 2009-04-22 | — | — | EP | disclosed |