Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD5 | P21918 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12334108 | 0.67 | DRD2 (0.33) | DRD2DRD1DRD4DRD5 | |
| SCHEMBL13326543 | 0.62 | — | — | |
| SCHEMBL5083188 | 0.62 | DRD2 (0.47) | DRD2DRD1DRD4DRD5 | |
| SCHEMBL13415331 | 0.61 | DRD2 (0.46) | DRD2DRD1DRD4DRD5 | |
| SCHEMBL15870923 | 0.60 | DRD2 (0.37) | DRD2DRD1DRD4DRD5 | |
| SCHEMBL5029738 | 0.58 | KDM1A (0.46) | DRD2 | |
| SCHEMBL6442527 | 0.58 | NOTUM (0.39) | — | |
| SCHEMBL18938898 | 0.57 | PARP1 (0.38) | — | |
| SCHEMBL15492687 | 0.57 | HRH1 (0.35) | DRD2DRD1DRD4DRD5 | |
| SCHEMBL15980338 | 0.57 | ALDH1A1 (0.30) | DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2050734-A1 | PENTADIENAMIDE DERIVATIVE | Kyowa Hakko Kirin Co., Ltd. (JP) | 2009-04-22 | — | — | EP | disclosed |