Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | DRD5 | P21918 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTR5A | P47898 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13415331 | 0.98 | DRD2 (0.46) | DRD2DRD1DRD4DRD5TSHR | |
| SCHEMBL13326543 | 0.95 | — | — | |
| SCHEMBL14195908 | 0.76 | DRD2 (0.40) | DRD2DRD1DRD4DRD5 | |
| SCHEMBL12363783 | 0.71 | DRD5 (0.66) | DRD2DRD1DRD4DRD5HTR5A | |
| SCHEMBL14489653 | 0.71 | DRD1 (0.61) | DRD2DRD1DRD4DRD5HTR5A | |
| SCHEMBL8221480 | 0.71 | TSHR (0.32) | TSHR | |
| SCHEMBL4753188 | 0.71 | RAB9A (0.32) | TSHRRAB9A | |
| SCHEMBL13397234 | 0.71 | TSHR (0.32) | TSHR | |
| SCHEMBL18723459 | 0.71 | TSHR (0.32) | TSHR | |
| SCHEMBL3079019 | 0.70 | BCL2L1 (0.39) | MEN1KMT2ANPC1USP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116490176-A | Pyrrole compounds and their use for the treatment of viral infections | 埃尼奥制药公司 | 2023-07-25 | — | — | CN | disclosed |
| WO-2022130270-A1 | N-(2-(4-CYANOTHIAZOLIDIN-3-YL)-2-OXOETHYL)- QUINOLINE-4-CARBOXAMIDES | ASTRAZENECA AB (SE) | 2022-06-23 | — | — | WO | disclosed |
| EP-2488486-B1 | HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES | LIGAND PHARM INC (US) | 2019-08-14 | — | — | EP | disclosed |
| EP-3016961-B1 | NOVEL RUTHENIUM CATALYSTS AND THEIR USE FOR ASYMMETRIC REDUCTION OF KETONES | BOEHRINGER INGELHEIM INT (DE) | 2017-11-15 | — | — | EP | disclosed |
| US-9622991-B2 | Hematopoietic growth factor mimetic small molecule compounds and their uses | LIGAND PHARMACEUTICALS INC. (US) | 2017-04-18 | — | — | US | disclosed |
| EP-2066648-B1 | SUBSTITUTED DIMETHYLCYCLOBUTYL COMPOUNDS, THEIR PREPARATION AND USE IN MEDICAMENTS | ESTEVE LABOR DR (ES) | 2017-04-12 | — | — | EP | disclosed |
| US-9144557-B2 | Hematopoietic growth factor mimetic small molecule compounds and their uses | LIGAND PHARMACEUTICALS INC. (US) | 2015-09-29 | — | — | US | disclosed |
| US-20150252043-A1 | HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES | CITIBANK, N.A., AS ADMINISTRATIVE AGENT | 2015-09-10 | — | — | US | disclosed |
| US-20140243324-A1 | USE OF HEMATOPOIETIC GROWTH FACTOR MIMETICS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2014-08-28 | — | — | US | disclosed |
| US-8778577-B2 | Colored composition, colored cured film, color filter, method for producing color filter, liquid crystal display device, solid-state imaging device, and novel dipyrromethene metal complex compound or tautomer thereof | FUJIFILM CORPORATION (JP) | 2014-07-15 | — | — | US | disclosed |
| US-7687500-B2 | Substituted oxetanes, method of making, and method of use thereof | THE UNIVERSITY OF CONNECTICUT (US) | 2010-03-30 | — | — | US | disclosed |
| EP-2060571-A1 | Insecticide iminoheterocycles | Bayer CropScience AG (DE) | 2009-05-20 | — | — | EP | disclosed |
| US-20080139566-A1 | SUBSTITUTED OXETANES, METHOD OF MAKING, AND METHOD OF USE THEREOF | HOWELL AMY R | 2008-06-12 | — | — | US | disclosed |
| US-20080139566-A1 | SUBSTITUTED OXETANES, METHOD OF MAKING, AND METHOD OF USE THEREOF | HOWELL AMY R | 2008-06-12 | — | — | US | disclosed |
| US-7351827-B2 | Substituted oxetanes, method of making, and method of use thereof | THE UNIVERSITY OF CONNECTICUT (US) | 2008-04-01 | — | — | US | disclosed |
| US-7351827-B2 | Substituted oxetanes, method of making, and method of use thereof | THE UNIVERSITY OF CONNECTICUT (US) | 2008-04-01 | — | — | US | disclosed |
| US-7314903-B2 | Catalyst system for the polymerization of olefins | BASELL POLYOLEFINE GMBH (DE) | 2008-01-01 | — | — | US | disclosed |
| US-20060094840-A1 | Catalyst system for the polymerization of olefins | BASSELL POLLYOLEFINE GMBH (DE) | 2006-05-04 | — | — | US | disclosed |
| EP-1611167-A2 | CATALYST SYSTEM FOR THE POLYMERIZATION OF OLEFINS | Basell Polyolefine GmbH (DE) | 2006-01-04 | — | — | EP | disclosed |
| WO-2004005360-A2 | CATALYST SYSTEM FOR THE POLYMERIZATION OF OLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2004-01-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140243324-A1 | USE OF HEMATOPOIETIC GROWTH FACTOR MIMETICS | HGF, EPOR, MPL | DRD2 4788/4885DRD1 4846/4885DRD4 4695/4885 |
| US-20080139566-A1 | SUBSTITUTED OXETANES, METHOD OF MAKING, AND METHOD OF USE THEREOF | PNP, TYMP, DHPS | DRD2 3328/4885DRD1 3007/4885DRD4 1430/4885 |
| US-20150252043-A1 | HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES | MPL, CSF3R, HGF | DRD2 4761/4885DRD1 4850/4885DRD4 4848/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.