Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 13/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3539061 | 0.89 | KDM4E (0.69) | HTR4KDM4EMEN1MAPTKMT2A | |
| SCHEMBL1163804 | 0.88 | KDM4E (0.51) | HTR4KDM4EMEN1MAPTKMT2A | |
| SCHEMBL3942580 | 0.84 | HTR4 (0.47) | HTR4KDM4EMEN1MAPTKMT2A | |
| SCHEMBL3538922 | 0.84 | HTR4 (0.47) | HTR4KDM4EMEN1MAPTKMT2A | |
| SCHEMBL13457657 | 0.82 | KDM4E (0.49) | HTR4KDM4EMEN1MAPTKMT2A | |
| SCHEMBL13881168 | 0.81 | KMT2A (0.47) | HTR4KDM4EMEN1MAPTKMT2A | |
| SCHEMBL10486812 | 0.81 | HTR4 (1.00) | HTR4 | |
| SCHEMBL12388397 | 0.81 | HTR4 (0.65) | HTR4KDM4EMEN1MAPTKMT2A | |
| SCHEMBL1560209 | 0.81 | HTR4 (0.64) | HTR4 | |
| SCHEMBL13880939 | 0.80 | KDM4E (0.53) | HTR4KDM4EMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009042711-A1 | POLO-LIKE KINASE INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-04-02 | — | — | WO | disclosed |