Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3539061 | 0.89 | KDM4E (0.69) | KDM4EMEN1MAPTKMT2AHTR4 | |
| SCHEMBL13880862 | 0.84 | ALDH1A1 (0.48) | KDM4EMEN1MAPTKMT2AHTR4 | |
| SCHEMBL13881173 | 0.84 | HRH3 (0.44) | KDM4EMEN1MAPTKMT2AHTR4 | |
| SCHEMBL13461317 | 0.82 | HTR4 (0.52) | KDM4EMEN1MAPTKMT2AHTR4 | |
| SCHEMBL13457545 | 0.82 | KDM4E (0.47) | KDM4EMEN1MAPTKMT2AHTR4 | |
| SCHEMBL13881180 | 0.81 | HTR4 (0.51) | KDM4EMEN1MAPTKMT2AHTR4 | |
| SCHEMBL3942580 | 0.81 | HTR4 (0.47) | KDM4EMEN1MAPTKMT2AHTR4 | |
| SCHEMBL3538922 | 0.81 | HTR4 (0.47) | KDM4EMEN1MAPTKMT2AHTR4 | |
| SCHEMBL13880913 | 0.80 | HTR4 (0.68) | KDM4EMEN1MAPTKMT2AHTR4 | |
| SCHEMBL1163804 | 0.80 | KDM4E (0.51) | KDM4EMEN1MAPTKMT2AHTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009042711-A1 | POLO-LIKE KINASE INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-04-02 | — | — | WO | disclosed |