Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 2/20 | 0.43 |
| ▸ | BRD4 | O60885 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.38 |
| ▸ | GABRE | P78334 | 1/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.38 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2425588 | 0.90 | GABRP (0.47) | NNMTBRD4TDP1MAPTIKBKB | |
| SCHEMBL5951698 | 0.88 | MAPK1 (0.46) | NNMTBRD4TDP1MAPTIKBKB | |
| SCHEMBL31413282 | 0.88 | MAPK1 (0.46) | NNMTBRD4TDP1MAPTIKBKB | |
| SCHEMBL7083041 | 0.88 | NNMT (0.50) | NNMTBRD4TDP1MAPTSIRT3 | |
| SCHEMBL5847055 | 0.85 | IKBKB (0.50) | BRD4TDP1MAPTIKBKBKDM4E | |
| SCHEMBL2427397 | 0.85 | KDM4E (0.54) | NNMTMAPTKDM4EALDH1A1GLA | |
| SCHEMBL4638397 | 0.83 | NNMT (0.47) | NNMTBRD4TDP1SIRT3GABRP | |
| SCHEMBL2858381 | 0.81 | DGAT1 (0.40) | NNMTBRD4TDP1MAPTIKBKB | |
| SCHEMBL5951820 | 0.81 | DGAT1 (0.40) | NNMTBRD4TDP1MAPTIKBKB | |
| SCHEMBL5952534 | 0.81 | CD44 (0.56) | NNMTBRD4TDP1IKBKBSIRT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009055077-A1 | TROPANE COMPOUNDS | EXELIXIS, INC. (US) | 2009-04-30 | — | — | WO | disclosed |