Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.37 |
| ▸ | BTK | Q06187 | 7/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13885493 | 0.94 | CREBBP (0.40) | CREBBPBTKHCAR3FLT3KDM4E | |
| SCHEMBL13885236 | 0.82 | CREBBP (0.43) | CREBBPKDM4EALDH1A1PTGER4 | |
| SCHEMBL12294367 | 0.78 | CREBBP (0.40) | RPS6KB1CREBBPBTKHCAR3FLT3 | |
| SCHEMBL2426799 | 0.77 | HCAR3 (0.55) | CREBBPHCAR3FLT3ALDH1A1 | |
| SCHEMBL2421680 | 0.77 | BTK (0.49) | BTKALDH1A1 | |
| SCHEMBL12294374 | 0.76 | CREBBP (0.43) | RPS6KB1CREBBPBTKHCAR3FLT3 | |
| SCHEMBL2425142 | 0.76 | JAK2 (0.49) | CREBBPBTKHCAR3ALDH1A1 | |
| SCHEMBL2426793 | 0.75 | HCAR3 (0.57) | CREBBPHCAR3FLT3 | |
| SCHEMBL2426534 | 0.75 | HCAR3 (0.57) | CREBBPHCAR3FLT3 | |
| SCHEMBL2423514 | 0.74 | ALDH1A1 (0.51) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009055077-A1 | TROPANE COMPOUNDS | EXELIXIS, INC. (US) | 2009-04-30 | — | — | WO | disclosed |