Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 1/20 | 0.38 |
| ▸ | HTR4 | Q13639 | 13/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MPO | P05164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3979382 | 0.81 | L3MBTL1 (0.36) | ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL3976415 | 0.77 | ALDH1A1 (0.36) | SSTR4ALDH1A1CYP2C19KMT2APOLB | |
| SCHEMBL3976822 | 0.76 | ALDH1A1 (0.38) | ALDH1A1POLB | |
| SCHEMBL3978510 | 0.74 | CNR2 (0.44) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL3976338 | 0.74 | CNR2 (0.45) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL3977688 | 0.74 | SSTR4 (0.44) | SSTR4ALDH1A1KMT2APDE4APDE4B | |
| SCHEMBL22186619 | 0.73 | HTR4 (0.41) | SSTR4HTR4ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL13886067 | 0.72 | ALDH1A1 (0.41) | SSTR4HTR4ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL13886066 | 0.69 | PTGDR2 (0.42) | CYP1A2CYP2C19KMT2A | |
| SCHEMBL15858711 | 0.68 | SSTR4 (0.50) | SSTR4HTR4ALDH1A1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009053799-A1 | NOVEL CANNABINOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESS FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-04-30 | — | — | WO | disclosed |