Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASE1 | P07998 | 1/20 | 0.36 |
| ▸ | TK2 | O00142 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TK1 | P04183 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.30 |
| ▸ | TYMS | P04818 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13166486 | 0.85 | TK1 (0.41) | TK2TK1LMNATYMS | |
| SCHEMBL14191193 | 0.82 | RNASE1 (0.34) | RNASE1POLBHSD17B10 | |
| SCHEMBL14191194 | 0.80 | TYMS (0.43) | POLBTYMS | |
| SCHEMBL12333750 | 0.80 | RNASE1 (0.42) | RNASE1POLBKDM4E | |
| SCHEMBL12958824 | 0.80 | POLB (0.38) | RNASE1POLB | |
| SCHEMBL13166488 | 0.79 | TK1 (0.49) | TK2TK1LMNA | |
| SCHEMBL23316644 | 0.77 | POLB (0.40) | RNASE1POLBLMNA | |
| SCHEMBL12087561 | 0.75 | DUT (0.47) | RNASE1 | |
| SCHEMBL26268704 | 0.75 | DUT (0.47) | RNASE1 | |
| SCHEMBL12015134 | 0.75 | DUT (0.47) | RNASE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7794943-B2 | Modified nucleic acid probes | AFFYMETRIX, INC. (US) | 2010-09-14 | — | — | US | disclosed |
| US-20090286690-A1 | Modified Nucleic Acid Probes | AFFYMETRIX, INC. (US) | 2009-11-19 | — | — | US | disclosed |