Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GALR3 | O60755 | 1/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 5/20 | 0.42 |
| ▸ | LDHA | P00338 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CFB | P00751 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13266029 | 0.81 | PDE5A (0.40) | ALDH1A1MAPTMAOAMAOBLMNA | |
| SCHEMBL2998606 | 0.75 | ALDH1A1 (0.54) | ALDH1A1MAPTKDM4EGALR3PTGER1 | |
| SCHEMBL13890313 | 0.69 | GAA (0.37) | ALDH1A1MAPTKDM4EPTGER1TDP1 | |
| SCHEMBL13363620 | 0.68 | PTGER1 (0.43) | PTGER1LDHACYP1A2CYP2C19 | |
| SCHEMBL2997463 | 0.67 | ALDH1A1 (0.46) | ALDH1A1MAPTKDM4EGALR3PTGER1 | |
| SCHEMBL14403826 | 0.67 | ALDH1A1 (0.44) | ALDH1A1MAPTKDM4EGALR3PTGER1 | |
| SCHEMBL17685042 | 0.66 | MAPT (0.42) | ALDH1A1MAPTKDM4EGALR3PTGER1 | |
| SCHEMBL9823342 | 0.61 | CYP1A1 (0.63) | ALDH1A1MAPTKDM4EGALR3SMN1; SMN2 | |
| SCHEMBL15284106 | 0.61 | PTGER1 (0.40) | ALDH1A1MAPTKDM4EGALR3PTGER1 | |
| SCHEMBL12375371 | 0.60 | PTGER1 (0.67) | PTGER1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090099179-A1 | COMPOUNDS FOR DISEASES AND DISORDERS | MYRIAD GENETICS, INCORPORATED (US) | 2009-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090099179-A1 | COMPOUNDS FOR DISEASES AND DISORDERS | CLN6, NLN, CLTC | ALDH1A1 1938/4885MAPT 657/4885KDM4E 4625/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.