Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 6/20 | 0.63 |
| ▸ | CYP1B1 | Q16678 | 6/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.57 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.57 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.57 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.57 |
| ▸ | CYP2A7 | P20853 | 1/20 | 0.57 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.57 |
| ▸ | CYP2F1 | P24903 | 1/20 | 0.57 |
| ▸ | CYP2C18 | P33260 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.57 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26319825 | 0.86 | ALDH1A1 (0.54) | CYP1A1CYP1B1ALDH1A1MAPTMEN1 | |
| SCHEMBL15609162 | 0.85 | ALDH1A1 (0.53) | CYP1A1CYP1B1ALDH1A1MAPTKDM4E | |
| SCHEMBL9823776 | 0.83 | CYP19A1 (0.56) | ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL5343313 | 0.81 | ALDH1A1 (0.62) | ALDH1A1KDM4EACHEHPGD | |
| SCHEMBL3957201 | 0.80 | ALDH1A1 (0.69) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3538483 | 0.79 | ALDH1A1 (0.47) | CYP1A1CYP1B1ALDH1A1MAPTKDM4E | |
| SCHEMBL8544868 | 0.78 | ALPL (0.53) | CYP1A1CYP1B1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL23743244 | 0.78 | CYP1A1 (1.00) | CYP1A1CYP1B1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL5342437 | 0.78 | ALDH1A1 (0.65) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3435518 | 0.77 | SMN1; SMN2 (0.51) | CYP1A1CYP1B1ALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0262873-B1 | N-TETRAZOLYL THIAZOLECARBOXAMIDE DERIVATIVES AND THEIR USE | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1991-08-21 | — | — | EP | disclosed |
| US-4879295-A | ANTIALLERGENS | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1989-11-07 | — | — | US | disclosed |
| EP-0262873-A1 | N-tetrazolyl thiazolecarboxamide derivatives and their use | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1988-04-06 | — | — | EP | disclosed |