SCHEMBL13890485

SCHEMBL13890485

O=C(CCCC1CCN(Cc2ccc(F)cc2)CC1)C1=NCCO1

nearest known ligand 0.52

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FAAH O00519 8/20 0.51
ACHE P22303 4/20 0.46
CHRM4 P08173 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13890509 0.90 FAAH (0.63) FAAHACHE
SCHEMBL13890457 0.88 FAAH (0.53) FAAHACHE
SCHEMBL13890511 0.87 FAAH (0.48) FAAHACHE
SCHEMBL13890491 0.86 FAAH (0.48) FAAH
SCHEMBL13890487 0.84 FAAH (0.48) FAAHACHE
SCHEMBL13890524 0.83 FAAH (0.44) FAAHACHE
SCHEMBL13890486 0.83 FAAH (0.52) FAAHACHECHRM4
SCHEMBL13890507 0.82 FAAH (0.50) FAAH
SCHEMBL13890490 0.82 FAAH (0.56) FAAHACHE
SCHEMBL13890459 0.82 FAAH (0.65) FAAHACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090111778-A1 2-Keto-Oxazoles as Modulators of Fatty Acid Amide Hydrolase JANSSEN PHARMACEUTICA N.V. (BE) 2009-04-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090111778-A1 2-Keto-Oxazoles as Modulators of Fatty Acid Amide Hydrolase FAAH, FAAH2, HCRTR2 FAAH 1/4885ACHE 1528/4885CHRM4 3691/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.