Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 13/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13890490 | 0.86 | FAAH (0.56) | FAAHACHE | |
| SCHEMBL13890459 | 0.85 | FAAH (0.65) | FAAHACHESIGMAR1 | |
| SCHEMBL13890485 | 0.84 | FAAH (0.51) | FAAHACHE | |
| SCHEMBL13890509 | 0.84 | FAAH (0.63) | FAAHACHE | |
| SCHEMBL13890457 | 0.83 | FAAH (0.53) | FAAHACHE | |
| SCHEMBL13890486 | 0.82 | FAAH (0.52) | FAAHACHESIGMAR1 | |
| SCHEMBL13890511 | 0.82 | FAAH (0.48) | FAAHACHE | |
| SCHEMBL13890524 | 0.81 | FAAH (0.44) | FAAHACHEMCHR1 | |
| SCHEMBL13890491 | 0.81 | FAAH (0.48) | FAAH | |
| SCHEMBL13890460 | 0.80 | FAAH (0.49) | FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090111778-A1 | 2-Keto-Oxazoles as Modulators of Fatty Acid Amide Hydrolase | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090111778-A1 | 2-Keto-Oxazoles as Modulators of Fatty Acid Amide Hydrolase | FAAH, FAAH2, HCRTR2 | FAAH 1/4885ACHE 1528/4885SIGMAR1 1111/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.