Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 16/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13890745 | 0.82 | LOXL2 (0.41) | LOXL2 | |
| SCHEMBL13875998 | 0.82 | LOXL2 (0.40) | GCKGPR119LOXL2 | |
| SCHEMBL1107301 | 0.81 | GCK (0.48) | GCKKCNH2 | |
| SCHEMBL1107335 | 0.80 | GCK (0.47) | GCKKCNH2 | |
| SCHEMBL1107318 | 0.77 | GCK (0.50) | GCKKCNH2 | |
| SCHEMBL13890809 | 0.75 | GRM5 (0.50) | — | |
| SCHEMBL13890753 | 0.74 | KCNK3 (0.48) | LOXL2 | |
| SCHEMBL4184514 | 0.73 | EPHX2 (0.51) | GPR119 | |
| SCHEMBL8049079 | 0.72 | ENPP2 (0.50) | — | |
| SCHEMBL2656722 | 0.72 | GCK (0.47) | GCKGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090099184-A1 | Substituted pyridineamide compounds useful as soluble epoxide hydrolase inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090099184-A1 | Substituted pyridineamide compounds useful as soluble epoxide hydrolase inhibitors | EPHX1, EPHX2, NCEH1 | GCK 4080/4885GPR119 2867/4885LOXL2 434/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.