Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNG2 | P59768 | 5/20 | 0.74 |
| ▸ | GNB1 | P62873 | 5/20 | 0.74 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.74 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.74 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.74 |
| ▸ | PHLPP2 | Q6ZVD8 | 2/20 | 0.59 |
| ▸ | MET | P08581 | 4/20 | 0.55 |
| ▸ | HGF | P14210 | 2/20 | 0.53 |
| ▸ | P2RY4 | P51582 | 7/20 | 0.52 |
| ▸ | P2RY2 | P41231 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | P2RY12 | Q9H244 | 4/20 | 0.49 |
| ▸ | P2RY6 | Q15077 | 3/20 | 0.49 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13891732 | 0.88 | GNG2 (0.86) | GNG2GNB1CYP1A2CYP2C9ALOX15 | |
| SCHEMBL2790949 | 0.85 | GNG2 (1.00) | GNG2GNB1CYP1A2CYP2C9ALOX15 | |
| SCHEMBL2778161 | 0.81 | GNG2 (1.00) | GNG2GNB1CYP1A2CYP2C9ALOX15 | |
| SCHEMBL29354288 | 0.81 | GNG2 (1.00) | GNG2GNB1CYP1A2CYP2C9ALOX15 | |
| SCHEMBL3029899 | 0.80 | GNG2 (0.97) | GNG2GNB1CYP1A2CYP2C9ALOX15 | |
| SCHEMBL13021512 | 0.80 | GNG2 (0.92) | GNG2GNB1CYP1A2CYP2C9ALOX15 | |
| SCHEMBL18867032 | 0.80 | GNG2 (0.71) | GNG2GNB1CYP1A2CYP2C9ALOX15 | |
| SCHEMBL9137161 | 0.79 | GNG2 (0.82) | GNG2GNB1CYP1A2CYP2C9ALOX15 | |
| SCHEMBL10488725 | 0.79 | GNG2 (0.84) | GNG2GNB1CYP1A2CYP2C9ALOX15 | |
| SCHEMBL10609900 | 0.78 | GNG2 (0.71) | GNG2GNB1CYP1A2CYP2C9ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009020677-A9 | COMPOSITIONS AND METHODS FOR INHIBITING G PROTEIN SIGNALING | UNIV ROCHESTER (US) | 2009-04-16 | — | — | WO | disclosed |
| WO-2009020677-A2 | COMPOSITIONS AND METHODS FOR INHIBITING G PROTEIN SIGNALING | UNIVERSITY OF ROCHESTER (US) | 2009-02-12 | — | — | WO | disclosed |