Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNG2 | P59768 | 5/20 | 0.82 |
| ▸ | GNB1 | P62873 | 5/20 | 0.82 |
| ▸ | P2RY4 | P51582 | 9/20 | 0.78 |
| ▸ | P2RY2 | P41231 | 8/20 | 0.78 |
| ▸ | PHLPP2 | Q6ZVD8 | 2/20 | 0.77 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.71 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.71 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.67 |
| ▸ | P2RY12 | Q9H244 | 7/20 | 0.64 |
| ▸ | P2RY6 | Q15077 | 4/20 | 0.64 |
| ▸ | ENTPD1 | P49961 | 2/20 | 0.64 |
| ▸ | MET | P08581 | 2/20 | 0.63 |
| ▸ | HGF | P14210 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13021512 | 0.94 | GNG2 (0.92) | GNG2GNB1P2RY4P2RY2PHLPP2 | |
| SCHEMBL3366752 | 0.92 | GNG2 (0.70) | GNG2GNB1P2RY4P2RY2PHLPP2 | |
| SCHEMBL2779595 | 0.90 | GNG2 (1.00) | GNG2GNB1P2RY4P2RY2PHLPP2 | |
| SCHEMBL13214098 | 0.90 | GNG2 (0.78) | GNG2GNB1P2RY4P2RY2PHLPP2 | |
| SCHEMBL29354288 | 0.90 | GNG2 (1.00) | GNG2GNB1P2RY4P2RY2PHLPP2 | |
| SCHEMBL13213975 | 0.90 | GNG2 (0.86) | GNG2GNB1P2RY4P2RY2PHLPP2 | |
| SCHEMBL2778161 | 0.90 | GNG2 (1.00) | GNG2GNB1P2RY4P2RY2PHLPP2 | |
| SCHEMBL791019 | 0.90 | GNG2 (0.85) | GNG2GNB1P2RY4P2RY2PHLPP2 | |
| SCHEMBL29357302 | 0.90 | GNG2 (0.85) | GNG2GNB1P2RY4P2RY2PHLPP2 | |
| SCHEMBL3030977 | 0.89 | GNG2 (0.76) | GNG2GNB1P2RY4P2RY2PHLPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9052324-B2 | Compounds and assays for controlling Wnt activity | ENZO BIOCHEM, INC. (US) | 2015-06-09 | — | — | US | disclosed |
| US-8968453-B2 | Anthrapyridone sulfonic acid compounds and their preparation methods and applications | Zhuhai Ninestar Management Co., Ltd. (CN) | 2015-03-03 | — | — | US | disclosed |
| US-8735533-B2 | Polymeric violet anthraquinone colorant compositions and methods for producing the same | MILLIKEN & COMPANY (US) | 2014-05-27 | — | — | US | disclosed |
| EP-2546309-A1 | ANTHRAPYRIDONE SULPHONIC ACID COMPOUNDS, PREPARATION AND USE THEREOF | Dalian University Of Technology (CN) | 2013-01-16 | — | — | EP | disclosed |
| US-20120322717-A9 | Compounds and assays for controlling Wnt activity | ENZO BIOCHEM, INC. | 2012-12-20 | — | — | US | disclosed |
| US-20100298200-A1 | Compounds and assays for controlling Wnt activity | LIU DAKAI | 2010-11-25 | — | — | US | disclosed |
| US-5416227-A | Dye salts of the anthraquinone dye series | CIBA-GEIGY CORPORATION (US) | 1995-05-16 | — | — | US | disclosed |
| EP-0445075-B1 | New dyestuff salts of the anthragquinone dye series | CIBA GEIGY AG (CH) | 1994-09-21 | — | — | EP | disclosed |
| EP-0445075-A1 | New dyestuff salts of the anthragquinone dye series | CIBA-GEIGY AG (CH) | 1991-09-04 | — | — | EP | disclosed |
| US-4322529-A | Tertiary-alkylamine salts of azine dyestuffs | CIBA-GEIGY CORPORATION (US) | 1982-03-30 | — | — | US | disclosed |
| US-RE29577-E | Anthraquinone dyestuffs | BAYER AKTIENGESELLSCHAFT (DT) | 1978-03-14 | — | — | US | disclosed |
| US-3994872-A | SOLUBILITY | CIBA-GEIGY CORPORATION (US) | 1976-11-30 | — | — | US | disclosed |
| US-3963763-A | Anthraquinone dyestuffs | BAYER AKTIENGESELLSCHAFT (DT) | 1976-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120322717-A9 | Compounds and assays for controlling Wnt activity | WNT1, WNT3A, WNT3 | GNG2 1082/4885GNB1 529/4885P2RY4 3888/4885 |
| US-20100298200-A1 | Compounds and assays for controlling Wnt activity | WNT1, WNT3A, WNT3 | GNG2 1082/4885GNB1 529/4885P2RY4 3888/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.