Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13891762 | 0.90 | MEN1 (0.47) | HTTLTB4R2KMT2AMEN1LMNA | |
| SCHEMBL13891773 | 0.83 | RAB9A (0.41) | RAB9AALDH1A1HTTNPC1JAK2 | |
| SCHEMBL4570417 | 0.81 | RAB9A (0.40) | RAB9AALDH1A1HTTNPC1JAK2 | |
| SCHEMBL13891756 | 0.80 | HSD17B1 (0.41) | RAB9AALDH1A1HTTNPC1JAK2 | |
| SCHEMBL15788736 | 0.79 | RAB9A (0.42) | RAB9AALDH1A1HTTNPC1JAK2 | |
| SCHEMBL14962289 | 0.79 | POLB (0.42) | RAB9AALDH1A1HTTNPC1JAK2 | |
| SCHEMBL13884014 | 0.79 | RAB9A (0.40) | RAB9AALDH1A1HTTNPC1JAK2 | |
| SCHEMBL148955 | 0.78 | HSD17B1 (0.45) | RAB9AALDH1A1HTTNPC1JAK2 | |
| SCHEMBL8581884 | 0.78 | HSD17B1 (0.45) | RAB9AALDH1A1HTTNPC1JAK2 | |
| SCHEMBL13484089 | 0.78 | HSD17B1 (0.45) | RAB9AALDH1A1HTTNPC1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7517625-B2 | Electrophotographic photoreceptor with improved durability and wear resistance; high quality latent images; crosslinked charge transport layer has a hardened monomer having three or more functional groups without charge transport structure and one with charge transport-containing (meth)acryloyloxy groups | RICOH COMPANY, LTD. (JP) | 2009-04-14 | — | — | US | disclosed |