Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 2/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | GPX4 | P36969 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13891773 | 0.97 | RAB9A (0.41) | HSD17B1HSD17B2LTB4R2ALDH1A1RAB9A | |
| Acrylic Acid SCHEMBL2282119 | 0.82 | HSD17B1 (0.46) | HSD17B1HSD17B2LTB4R2ALDH1A1RAB9A | |
| SCHEMBL12934616 | 0.82 | BCL2 (0.42) | HSD17B1HSD17B2MEN1KMT2AFFAR1 | |
| SCHEMBL12571982 | 0.82 | LMNA (0.38) | LTB4R2ALDH1A1HTTLMNA | |
| SCHEMBL22148976 | 0.81 | LTB4R2 (0.39) | HSD17B1HSD17B2LTB4R2ALDH1A1RAB9A | |
| SCHEMBL14410123 | 0.80 | ALDH1A1 (0.42) | ALDH1A1HTTKDM4EMEN1KMT2A | |
| SCHEMBL20733435 | 0.80 | ALDH1A1 (0.42) | ALDH1A1HTTKDM4EMEN1KMT2A | |
| SCHEMBL13891757 | 0.80 | RAB9A (0.41) | HSD17B1HSD17B2LTB4R2ALDH1A1RAB9A | |
| SCHEMBL13569469 | 0.80 | ALOX5 (0.40) | HSD17B1HSD17B2LTB4R2NR1H4HPGD | |
| SCHEMBL20733436 | 0.80 | THRB (0.36) | ALDH1A1RAB9ANPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7517625-B2 | Electrophotographic photoreceptor with improved durability and wear resistance; high quality latent images; crosslinked charge transport layer has a hardened monomer having three or more functional groups without charge transport structure and one with charge transport-containing (meth)acryloyloxy groups | RICOH COMPANY, LTD. (JP) | 2009-04-14 | — | — | US | disclosed |