Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.32 |
| ▸ | HSD11B2 | P80365 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13891774 | 0.97 | ADORA3 (0.37) | ADORA3NPC1RAB9AMEN1KMT2A | |
| SCHEMBL13891747 | 0.84 | ITGB1 (0.35) | ADORA3NPC1RAB9AHRH3MEN1 | |
| SCHEMBL9915744 | 0.81 | ADORA3 (0.40) | ADORA3KMT2APPARAESR1ESR2 | |
| SCHEMBL13891765 | 0.81 | ADORA3 (0.37) | ADORA3NPC1RAB9AMEN1KMT2A | |
| SCHEMBL13879209 | 0.80 | ESR1 (0.44) | ADORA3RAB9AALDH1A1ESR1ESR2 | |
| SCHEMBL10005769 | 0.80 | ESR1 (0.44) | ADORA3RAB9AALDH1A1ESR1ESR2 | |
| SCHEMBL12149050 | 0.79 | THRB (0.39) | ADORA3CNR2CNR1ALDH1A1 | |
| SCHEMBL12151362 | 0.78 | CNR2 (0.40) | ADORA3CNR2CNR1 | |
| SCHEMBL12755179 | 0.77 | ADORA3 (0.43) | ADORA3KMT2APPARAALDH1A1ESR1 | |
| SCHEMBL9915742 | 0.77 | ADORA3 (0.43) | ADORA3KMT2APPARAALDH1A1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7517625-B2 | Electrophotographic photoreceptor with improved durability and wear resistance; high quality latent images; crosslinked charge transport layer has a hardened monomer having three or more functional groups without charge transport structure and one with charge transport-containing (meth)acryloyloxy groups | RICOH COMPANY, LTD. (JP) | 2009-04-14 | — | — | US | disclosed |