Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 3/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.35 |
| ▸ | CNR2 | P34972 | 4/20 | 0.34 |
| ▸ | CNR1 | P21554 | 3/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.34 |
| ▸ | HSD11B2 | P80365 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTR1E | P28566 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13891747 | 0.97 | ITGB1 (0.35) | ADORA3NPC1RAB9AESR1ESR2 | |
| SCHEMBL13891774 | 0.83 | ADORA3 (0.37) | ADORA3NPC1RAB9AESR1ESR2 | |
| SCHEMBL2602480 | 0.81 | CA1 (0.42) | ADORA3ESR1ESR2CNR2CNR1 | |
| SCHEMBL9915790 | 0.81 | L3MBTL1 (0.42) | NPC1RAB9ACNR2CNR1KMT2A | |
| SCHEMBL13891772 | 0.81 | ADORA3 (0.35) | ADORA3NPC1RAB9AESR1ESR2 | |
| SCHEMBL13765741 | 0.79 | HSD11B1 (0.41) | ADORA3ESR1ESR2HSD11B1HSD11B2 | |
| SCHEMBL5452904 | 0.79 | ESR1 (0.48) | ADORA3ESR1ESR2HSD11B1HSD11B2 | |
| SCHEMBL13879208 | 0.79 | ESR1 (0.48) | ADORA3ESR1ESR2HSD11B1HSD11B2 | |
| SCHEMBL21168792 | 0.79 | ESR1 (0.48) | ADORA3ESR1ESR2HSD11B1HSD11B2 | |
| SCHEMBL12306231 | 0.79 | ESR1 (0.48) | ADORA3ESR1ESR2HSD11B1HSD11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7517625-B2 | Electrophotographic photoreceptor with improved durability and wear resistance; high quality latent images; crosslinked charge transport layer has a hardened monomer having three or more functional groups without charge transport structure and one with charge transport-containing (meth)acryloyloxy groups | RICOH COMPANY, LTD. (JP) | 2009-04-14 | — | — | US | disclosed |