Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 8/20 | 0.39 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
| ▸ | GSR | P00390 | 1/20 | 0.35 |
| ▸ | Q9HBH1 | 1/20 | 0.33 | |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.33 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.33 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10047161 | 0.88 | FOLH1 (0.40) | CPB2RNPEPFOLH1SIRT6SIRT1 | |
| SCHEMBL13891963 | 0.88 | FOLH1 (0.40) | CPB2RNPEPFOLH1SIRT6SIRT1 | |
| SCHEMBL22859968 | 0.88 | FOLH1 (0.40) | CPB2RNPEPFOLH1SIRT6SIRT1 | |
| SCHEMBL19483433 | 0.86 | CPB2 (0.41) | CPB2RNPEPFOLH1SIRT6SIRT1 | |
| SCHEMBL19483432 | 0.86 | CPB2 (0.41) | CPB2RNPEPFOLH1SIRT6SIRT1 | |
| SCHEMBL19483311 | 0.84 | FOLH1 (0.37) | CPB2RNPEPFOLH1SIRT6SIRT1 | |
| SCHEMBL19483319 | 0.84 | FOLH1 (0.37) | CPB2RNPEPFOLH1SIRT6SIRT1 | |
| SCHEMBL22375523 | 0.81 | FOLH1 (0.40) | CPB2RNPEPFOLH1SIRT6SIRT1 | |
| SCHEMBL25570523 | 0.81 | FOLH1 (0.40) | CPB2RNPEPFOLH1SIRT6SIRT1 | |
| SCHEMBL20402783 | 0.79 | CPB2 (0.41) | CPB2RNPEPFOLH1SIRT6SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10927139-B2 | Chemically cleavable group | TAGWORKS PHARMACEUTICALS B.V. (NL) | 2021-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10927139-B2 | Chemically cleavable group | SQLE, CTRL, ENO1 | CPB2 50/4885RNPEP 393/4885FOLH1 776/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.