Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Malonic Acid SCHEMBL9760918 | 0.90 | LMNA (0.62) | LMNACYP2C19HIF1A | |
| Malonic Acid SCHEMBL11132766 | 0.90 | LMNA (0.48) | LMNACYP2C19HIF1A | |
| Malonic Acid SCHEMBL9526080 | 0.88 | LMNA (0.55) | LMNACYP2C19HIF1A | |
| SCHEMBL1389273 | 0.85 | LMNA (0.67) | LMNACYP2C19HIF1A | |
| SCHEMBL681515 | 0.83 | LMNA (0.50) | LMNACYP2C19HIF1A | |
| Malonic Acid SCHEMBL9760605 | 0.83 | LMNA (0.48) | LMNACYP2C19HIF1A | |
| Malonic Acid SCHEMBL9761104 | 0.83 | LMNA (0.51) | LMNACYP2C19HIF1A | |
| Malonic Acid SCHEMBL11131920 | 0.81 | LMNA (0.50) | LMNACYP2C19HIF1A | |
| Adipic Acid SCHEMBL11497321 | 0.80 | LMNA (0.44) | LMNACYP2C19HIF1A | |
| SCHEMBL9843094 | 0.80 | LMNA (0.46) | LMNACYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5073362-A | DICARBOXYLIC ACID-BIS(3,5-DICARBAMOYL-2,4,6-TRIIODOANILIDES) AND X-RAY CONTRAST MEDIA CONTAINING THEM | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-12-17 | — | — | US | disclosed |