SCHEMBL1389296

SCHEMBL1389296

C1=CC2CCC1C2.CCOc1ccc(C=CC(=O)O)c(C)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.47
ALDH1A1 P00352 5/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
GAA P10253 3/20 0.45
ESR1 P03372 3/20 0.42
PPARG P37231 1/20 0.42
PPARD Q03181 1/20 0.42
PPARA Q07869 1/20 0.42
HPGD P15428 2/20 0.42
TSHR P16473 2/20 0.42
HSD17B10 Q99714 2/20 0.42
CYP1A2 P05177 1/20 0.42
POLB P06746 2/20 0.41
USP2 O75604 1/20 0.40
LMNA P02545 1/20 0.40
MAPT P10636 1/20 0.40
GLA P06280 1/20 0.39
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
CYP1A1 P04798 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3217320 0.91 KDM4E (0.47) KDM4EALDH1A1SMN1; SMN2GAAESR1
SCHEMBL211526 0.88 PPARG (0.40) KDM4EALDH1A1SMN1; SMN2GAAESR1
SCHEMBL213132 0.87 THRB (0.44) ALDH1A1SMN1; SMN2GAAESR1MAPT
SCHEMBL1389238 0.82 ESR1 (0.44) KDM4EALDH1A1SMN1; SMN2GAAESR1
SCHEMBL213294 0.79 TDO2 (0.43) KDM4ESMN1; SMN2ESR1CYP1A1CYP1B1
SCHEMBL16440078 0.78 PTGER4 (0.45) ALDH1A1SMN1; SMN2GAAMAPTMEN1
SCHEMBL213053 0.77 THRB (0.44) KDM4EALDH1A1SMN1; SMN2GAAMAPT
SCHEMBL3689444 0.77 PTGER1 (0.52) KDM4EALDH1A1SMN1; SMN2GAAPOLB
SCHEMBL27841592 0.77 ESR1 (0.37) KDM4EALDH1A1SMN1; SMN2GAAESR1
SCHEMBL16910608 0.77 PTGER3 (0.55) KDM4EALDH1A1LMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2386588-B1 NORBORNENE POLYMER INCLUDING PHOTOREACTIVE FUNCTIONAL GROUP THAT HAS HALOGEN SUBSTITUENT, METHOD FOR PREPARING THE SAME, AND ALIGNMENT LAYER USING THE SAME LG CHEMICAL LTD (KR) 2015-08-19 EP disclosed
US-8343597-B2 Norbornene polymer comprising photoreactive functional group having halogen substituent group, process for preparing the same, and alignment layer using the same LG CHEM, LTD. (KR) 2013-01-01 US disclosed
US-8231946-B2 Norbornene polymer comprising photoreactive functional group having halogen substituent group, process for preparing the same, and alignment layer using the same LG CHEM, LTD. (KR) 2012-07-31 US disclosed
US-20120009359-A1 NORBORNENE POLYMER COMPRISING PHOTOREACTIVE FUNCTIONAL GROUP HAVING HALOGEN SUBSTITUENT GROUP, PROCESS FOR PREPARING THE SAME, AND ALIGNMENT LAYER USING THE SAME LG CHEM, LTD. (KR) 2012-01-12 US disclosed
EP-2386588-A2 NORBORNENE POLYMER INCLUDING PHOTOREACTIVE FUNCTIONAL GROUP THAT HAS HALOGEN SUBSTITUENT, METHOD FOR PREPARING THE SAME, AND ALIGNMENT LAYER USING THE SAME LG Chem, Ltd. (KR) 2011-11-16 EP disclosed
US-8038662-B2 Incontinence article in the form of pants PAUL HARTMANN AKTIENGESELLSCHAFT (DE) 2011-10-18 US disclosed
US-20110213048-A1 NORBORNENE POLYMER COMPRISING PHOTOREACTIVE FUNCTIONAL GROUP HAVING HALOGEN SUBSTITUENT GROUP, PROCESS FOR PREPARING THE SAME, AND ALIGNMENT LAYER USING THE SAME LG CHEM, LTD. (KR) 2011-09-01 US disclosed
US-20100068419-A1 RETARDATION FILM, A METHOD FOR PREPARING RETARDATION FILM AND POLARIZER COMPRISING THE RETARDATION FILM LG CHEM, LTD. (KR) 2010-03-18 US disclosed
WO-2008130186-A2 A RETARDATION FILM, A METHOD FOR PREPARING RETARDATION FILM AND POLARIZER COMPRISING THE RETARDATION FILM LG CHEM, LTD. (KR) 2008-10-30 WO disclosed