SCHEMBL211526

SCHEMBL211526

C1=CC2CCC1C2.C=CCOc1ccc(C=CC(=O)O)c(C)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 1/20 0.40
PPARD Q03181 1/20 0.40
PPARA Q07869 1/20 0.40
ESR1 P03372 2/20 0.39
PTPN1 P18031 3/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
LMNA P02545 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
ALDH1A1 P00352 4/20 0.37
GAA P10253 3/20 0.37
HPGD P15428 1/20 0.37
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
TP53 P04637 1/20 0.36
MAPT P10636 2/20 0.36
KDM4E B2RXH2 3/20 0.35
SLC5A1 P13866 1/20 0.35
SLC5A2 P31639 1/20 0.35
POLB P06746 1/20 0.35
PKM P14618 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8387242 0.89 PPARG (0.47) PPARGPPARDPPARAESR1PTPN1
SCHEMBL8387240 0.89 PPARG (0.47) PPARGPPARDPPARAESR1PTPN1
SCHEMBL1389296 0.88 KDM4E (0.47) PPARGPPARDPPARAESR1SMN1; SMN2
SCHEMBL3217320 0.86 KDM4E (0.47) PPARGPPARDPPARAESR1SMN1; SMN2
SCHEMBL213132 0.84 THRB (0.44) ESR1SMN1; SMN2ALDH1A1GAANPC1
SCHEMBL1389238 0.77 ESR1 (0.44) PPARGPPARDPPARAESR1SMN1; SMN2
SCHEMBL213294 0.77 TDO2 (0.43) ESR1SMN1; SMN2KDM4E
SCHEMBL213053 0.75 THRB (0.44) SMN1; SMN2ALDH1A1GAANPC1RAB9A
SCHEMBL8387413 0.74 HPGD (0.44) PTPN1SMN1; SMN2LMNANPSR1GAA
SCHEMBL8387418 0.74 HPGD (0.44) PTPN1SMN1; SMN2LMNANPSR1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140192299-A1 COMPOSITION FOR LIQUID CRYSTAL ALIGNMENT LAYER, PREPARATION METHOD OF LIQUID CRYSTAL ALIGNMENT LAYER USING THE SAME, AND OPTICAL FILM COMPRISING THE LIQUID CRYSTAL ALIGNMENT LAYER LG CHEM, LTD. (KR) 2014-07-10 US disclosed
US-8703253-B2 Composition for liquid crystal alignment layer, preparation method of liquid crystal alignment layer using the same, and optical film comprising the liquid crystal alignment layer LG CHEM, LTD. (KR) 2014-04-22 US disclosed
US-8089585-B2 Optical film, preparation method of the same, and liquid crystal display comprising the same LG CHEM, LTD. (KR) 2012-01-03 US disclosed
US-20110051050-A1 OPTICAL FILM, PREPARATION METHOD OF THE SAME, AND LIQUID CRYSTAL DISPLAY COMPRISING THE SAME LG CHEM, LTD. (KR) 2011-03-03 US disclosed
US-20110043731-A1 COMPOSITION FOR LIQUID CRYSTAL ALIGNMENT LAYER, PREPARATION METHOD OF LIQUID CRYSTAL ALIGNMENT LAYER USING THE SAME, AND OPTICAL FILM COMPRISING THE LIQUID CRYSTAL ALIGNMENT LAYER LG CHEM, LTD. (KR) 2011-02-24 US disclosed
US-20100296032-A1 OPTICAL FILM, PREPARATION METHOD OF THE SAME, AND LIQUID CRYSTAL DISPLAY COMPRISING THE SAME JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2010-11-25 US disclosed
US-20100182547-A1 Optical film, preparation method of the same, and liquid crystal display comprising the same LG CHEM, LTD. (KR) 2010-07-22 US disclosed
WO-2009091225-A2 COMPOSITION FOR LIQUID CRYSTAL ALIGNMENT LAYER, PREPARATION METHOD OF LIQUID CRYSTAL ALIGNMENT LAYER USING THE SAME, AND OPTICAL FILM COMPRISING THE LIQUID CRYSTAL ALIGNMENT LAYER LG CHEM, LTD. (KR) 2009-07-23 WO disclosed
WO-2009091227-A2 OPTICAL FILM, PREPARATION METHOD OF THE SAME, AND LIQUID CRYSTAL DISPLAY COMPRISING THE SAME LG CHEM, LTD. (KR) 2009-07-23 WO disclosed
WO-2009091224-A2 OPTICAL FILM, PREPARATION METHOD OF THE SAME, AND LIQUID CRYSTAL DISPLAY COMPRISING THE SAME LG CHEM, LTD. (KR) 2009-07-23 WO disclosed