Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD44 | P16070 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.31 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.31 |
| ▸ | BAD | Q92934 | 1/20 | 0.31 |
| ▸ | PNMT | P11086 | 1/20 | 0.30 |
| ▸ | TYR | P14679 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10348095 | 0.74 | CD44 (0.48) | CD44ALOX15CYP3A4ALDH1A1HPGD | |
| SCHEMBL12328333 | 0.74 | — | — | |
| Ammonia Solution, Strong SCHEMBL11303343 | 0.72 | — | — | |
| SCHEMBL10348098 | 0.72 | CD44 (0.47) | CD44ALOX15CYP3A4ALDH1A1HPGD | |
| SCHEMBL207995 | 0.70 | ALDH1A1 (0.41) | CD44CYP3A4ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL1143178 | 0.70 | CYP1A2 (0.40) | ALOX15CYP3A4ALDH1A1MEN1GAA | |
| SCHEMBL4924539 | 0.69 | CD44 (0.44) | CD44ALOX15CYP3A4ALDH1A1HPGD | |
| SCHEMBL8527304 | 0.69 | CD44 (0.44) | CD44ALOX15CYP3A4ALDH1A1HPGD | |
| SCHEMBL20938678 | 0.68 | ALOX15 (0.45) | CD44ALOX15CYP3A4ALDH1A1HPGD | |
| Naphthalene SCHEMBL10399081 | 0.67 | CYP3A4 (0.44) | CD44ALOX15CYP3A4ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2048132-A1 | Tetrahydro-naphthalene and urea derivatives | Xention Limited (GB) | 2009-04-15 | — | — | EP | disclosed |
| EP-1670761-B1 | TETRAHYDRO-NAPHTHALENE AND UREA DERIVATIVES | XENTION LTD (GB) | 2009-01-28 | — | — | EP | disclosed |