Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 8/20 | 0.33 |
| ▸ | DRD1 | P21728 | 8/20 | 0.33 |
| ▸ | DRD5 | P21918 | 7/20 | 0.33 |
| ▸ | DRD3 | P35462 | 6/20 | 0.33 |
| ▸ | DRD4 | P21917 | 5/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPN | P05981 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11503342 | 0.72 | CYP1A2 (0.42) | CYP1A2CYP2A6DRD2DRD1DRD5 | |
| SCHEMBL13893141 | 0.70 | CD44 (0.38) | ALOX15HSD17B10TSHRMEN1KMT2A | |
| SCHEMBL2521301 | 0.70 | CYP1A2 (0.46) | CYP1A2CYP2A6DRD2DRD1DRD5 | |
| SCHEMBL18091536 | 0.69 | CYP1A2 (0.50) | CYP1A2CYP2A6DRD2DRD1DRD5 | |
| SCHEMBL8131373 | 0.69 | CYP1A2 (0.39) | CYP1A2CYP2A6ALOX15MAOAMAOB | |
| SCHEMBL30640267 | 0.69 | CYP1A2 (0.39) | CYP1A2CYP2A6ALOX15MAOAMAOB | |
| SCHEMBL14701239 | 0.68 | TRPA1 (0.36) | ALDH1A1 | |
| SCHEMBL109650 | 0.67 | CYP1A2 (0.62) | CYP1A2CYP2A6DRD2DRD1DRD5 | |
| SCHEMBL29881712 | 0.67 | — | — | |
| SCHEMBL22081972 | 0.67 | CYP1A2 (0.62) | CYP1A2CYP2A6DRD2DRD1DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9040225-B2 | Developable bottom antireflective coating composition and pattern forming method using thereof | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2015-05-26 | — | — | US | disclosed |
| US-8999624-B2 | Developable bottom antireflective coating composition and pattern forming method using thereof | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2015-04-07 | — | — | US | disclosed |
| US-20150050601-A1 | DEVELOPABLE BOTTOM ANTIREFLECTIVE COATING COMPOSITION AND PATTERN FORMING METHOD USING THEREOF | GLOBALFOUNDRIES U.S. INC. | 2015-02-19 | — | — | US | disclosed |
| US-8715907-B2 | Developable bottom antireflective coating compositions for negative resists | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2014-05-06 | — | — | US | disclosed |
| US-20130040238-A1 | DEVELOPABLE BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS FOR NEGATIVE RESISTS | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2013-02-14 | — | — | US | disclosed |
| US-8303844-B2 | Benzo[f]chrome any pyrano[3,2-f]chrome derivatives for use in liquid crystal media | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-11-06 | — | — | US | disclosed |
| US-20110043746-A1 | BENZO[F]CHROME ANY PYRANO[3,2-F]CHROME DERIVATIVES FOR USE IN LIQUID CRYSTAL MEDIA | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-02-24 | — | — | US | disclosed |
| WO-1998049149-A1 | PREPARATION OF MIBEFRADIL I | F. HOFFMANN-LA ROCHE AG (CH) | 1998-11-05 | — | — | WO | disclosed |
| WO-1998049148-A1 | PREPARATION OF MIBEFRADIL II | F. HOFFMANN-LA ROCHE AG (CH) | 1998-11-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110043746-A1 | BENZO[F]CHROME ANY PYRANO[3,2-F]CHROME DERIVATIVES FOR USE IN LIQUID CRYSTAL MEDIA | CHRM1, F12, CTRB2 | CYP1A2 99/4885CYP2A6 538/4885DRD2 654/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.