SCHEMBL138937

SCHEMBL138937

CC(=O)[C@@]1(O)CC[C@H]2[C@@H]3CC=C4CC(O)CC[C@]4(C)[C@H]3CC[C@@]21C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SHBG P04278 6/20 1.00
CYP17A1 P05093 5/20 0.73
ALDH1A1 P00352 1/20 0.70
CYP2C9 P11712 1/20 0.70
HIF1A Q16665 1/20 0.70
G6PD P11413 4/20 0.61
LMNA P02545 3/20 0.61
SERPINA6 P08185 3/20 0.61
MEN1 O00255 1/20 0.61
GUSB P08236 1/20 0.61
CYP3A4 P08684 1/20 0.61
PMP22 Q01453 1/20 0.61
KMT2A Q03164 1/20 0.61
GPBAR1 Q8TDU6 1/20 0.61
TSHR P16473 1/20 0.61
SMN1; SMN2 Q16637 1/20 0.61
ESR1 P03372 1/20 0.58
AR P10275 1/20 0.58
ESR2 Q92731 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17776491 1.00 SHBG (1.00) SHBGCYP17A1ALDH1A1CYP2C9HIF1A
SCHEMBL142941 1.00 SHBG (1.00) SHBGCYP17A1ALDH1A1CYP2C9HIF1A
SCHEMBL27808104 1.00 SHBG (1.00) SHBGCYP17A1ALDH1A1CYP2C9HIF1A
SCHEMBL658688 1.00 SHBG (1.00) SHBGCYP17A1ALDH1A1CYP2C9HIF1A
SCHEMBL735471 1.00 SHBG (1.00) SHBGCYP17A1ALDH1A1CYP2C9HIF1A
SCHEMBL18373712 1.00 SHBG (1.00) SHBGCYP17A1ALDH1A1CYP2C9HIF1A
SCHEMBL20457510 1.00 SHBG (1.00) SHBGCYP17A1ALDH1A1CYP2C9HIF1A
SCHEMBL27633183 1.00 SHBG (1.00) SHBGCYP17A1ALDH1A1CYP2C9HIF1A
Sulfuric Acid SCHEMBL1576876 0.96 SHBG (0.91) SHBGCYP17A1ALDH1A1CYP2C9HIF1A
SCHEMBL31086698 0.92 SHBG (0.85) SHBGCYP17A1ALDH1A1CYP2C9HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1408 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260140124-A1 PCOS STRATIFICATION THE UNIVERSITY OF BIRMINGHAM (GB) 2026-05-21 US claimed
EP-4740024-A1 ENDOMETRIOSIS MARKERS AND METHODS OF DIAGNOSING ENDOMETRIOSIS The University Court Of The University of Edinburgh (GB) 2026-05-13 EP claimed
CN-122017085-A Method for simultaneously detecting multiple steroid hormones in serum 北京大学第三医院(北京大学第三临床医学院) 2026-05-12 CN claimed
EP-4605743-A1 PCOS STRATIFICATION The University of Birmingham (GB) 2025-08-27 EP claimed
EP-3486648-B1 MASS SPECTROMETRY ASSAY FOR CONGENITAL ADRENAL HYPERPLASIA QUEST DIAGNOSTICS INVEST INC (US) 2025-04-30 EP claimed
WO-2025008638-A1 ENDOMETRIOSIS MARKERS AND METHODS OF DIAGNOSING ENDOMETRIOSIS THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH (GB) 2025-01-09 WO claimed
CN-115343398-B Kit and method for simultaneously measuring multiple steroid hormones in serum 吉林大学第一医院 2024-12-24 CN claimed
CN-119125354-A Method and kit for measuring various steroid hormones in body fluid by liquid chromatography-mass spectrometry technology 浙江博圣生物技术股份有限公司 2024-12-13 CN claimed
CN-119125357-A Kit for simultaneously detecting multiple steroid hormones in dried blood spots based on liquid chromatography-mass spectrometry and application of kit 浙江博圣生物技术股份有限公司 2024-12-13 CN claimed
CN-118961985-A Kit and method for simultaneously detecting 18 steroid hormones based on double-derivative technology 上海万子健医学检验实验室有限公司 2024-11-15 CN claimed
WO-1999040203-A1 YEAST STRAINS WITH INTERRUPTED ATF2 GENE AND USES HOECHST MARION ROUSSEL (FR) 1999-08-12 WO claimed
EP-0594581-B1 PRODUCTION OF GLYCOSIDES, ESPECIALLY OF STEROIDAL GLYCOSIDES KLEMKE RUDOLF ERICH (DE) 1998-07-01 EP claimed
EP-0649472-A4 FUSION PROTEINS COMPRISING EUKARYOTIC CYTOCHROME P450 FUSED TO A REDUCTASE. UNIV TEXAS (US) 1997-03-19 EP claimed
EP-0649472-A1 FUSION PROTEINS COMPRISING EUKARYOTIC CYTOCHROME P450 FUSED TO A REDUCTASE THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1995-04-26 EP claimed
EP-0594581-A1 PRODUCTION OF GLYCOSIDES, ESPECIALLY OF STEROIDAL GLYCOSIDES Klemke, Rudolf Erich, Dipl.-Chem. (DE) 1994-05-04 EP claimed
WO-1994001568-A1 FUSION PROTEINS COMPRISING EUKARYOTIC CYTOCHROME P450 FUSED TO A REDUCTASE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1994-01-20 WO claimed
US-5137822-A Transformed yeasts having steroid-hydroxylase activity and process for hydroxylation of steroids using the said transformed yeasts DIRECTOR-GENERAL OF AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY AN ORGAN OF THE MINISTRY OF INDUSTRIAL TRADE AND INDUSTRY OF JAPAN (JP) 1992-08-11 US claimed
WO-1992013076-A1 METHODS AND COMPOSITIONS FOR THE EXPRESSION OF BIOLOGICALLY ACTIVE EUKARYOTIC CYTOCHROME P450S IN BACTERIA BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1992-08-06 WO claimed
WO-1991011452-A1 PRODUCTION OF GLYCOSIDES, ESPECIALLY OF STEROIDAL GLYCOSIDES 'HARRIER' GMBH GESELLSCHAFT FÜR DEN VERTRIEB MEDIZINISCHER UND TECHNISCHER GERÄTE (DE) 1991-08-08 WO claimed
US-4321208-A Preparation of directly iodinated steroid hormones and related compounds SAHADEVAN VELAYUDHAN 1982-03-23 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260140124-A1 PCOS STRATIFICATION HSD17B3, AKR1C3, HSD17B11 SHBG 34/4885CYP17A1 15/4885ALDH1A1 463/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.