Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 6/20 | 1.00 |
| ▸ | CYP17A1 | P05093 | 5/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.70 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.70 |
| ▸ | G6PD | P11413 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | SERPINA6 | P08185 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | GUSB | P08236 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | ESR1 | P03372 | 1/20 | 0.58 |
| ▸ | AR | P10275 | 1/20 | 0.58 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL138937 | 1.00 | SHBG (1.00) | SHBGCYP17A1ALDH1A1CYP2C9HIF1A | |
| SCHEMBL142941 | 1.00 | SHBG (1.00) | SHBGCYP17A1ALDH1A1CYP2C9HIF1A | |
| SCHEMBL27808104 | 1.00 | SHBG (1.00) | SHBGCYP17A1ALDH1A1CYP2C9HIF1A | |
| SCHEMBL658688 | 1.00 | SHBG (1.00) | SHBGCYP17A1ALDH1A1CYP2C9HIF1A | |
| SCHEMBL735471 | 1.00 | SHBG (1.00) | SHBGCYP17A1ALDH1A1CYP2C9HIF1A | |
| SCHEMBL18373712 | 1.00 | SHBG (1.00) | SHBGCYP17A1ALDH1A1CYP2C9HIF1A | |
| SCHEMBL20457510 | 1.00 | SHBG (1.00) | SHBGCYP17A1ALDH1A1CYP2C9HIF1A | |
| SCHEMBL27633183 | 1.00 | SHBG (1.00) | SHBGCYP17A1ALDH1A1CYP2C9HIF1A | |
| Sulfuric Acid SCHEMBL1576876 | 0.96 | SHBG (0.91) | SHBGCYP17A1ALDH1A1CYP2C9HIF1A | |
| SCHEMBL31086698 | 0.92 | SHBG (0.85) | SHBGCYP17A1ALDH1A1CYP2C9HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10040816-B2 | Antagonists of CB1 receptor | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2018-08-07 | — | — | US | disclosed |
| US-10040816-B2 | Antagonists of CB1 receptor | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2018-08-07 | — | — | US | disclosed |
| US-20160145294-A1 | Antagonists of CB1 Receptor | INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) | 2016-05-26 | — | — | US | disclosed |
| US-20160145294-A1 | Antagonists of CB1 Receptor | INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) | 2016-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10040816-B2 | Antagonists of CB1 receptor | CNR2, CNR1, GPR18 | SHBG 593/4885CYP17A1 1317/4885ALDH1A1 2761/4885 |
| US-20160145294-A1 | Antagonists of CB1 Receptor | CNR2, CNR1, GPR18 | SHBG 593/4885CYP17A1 1317/4885ALDH1A1 2761/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.