Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 6/20 | 1.00 |
| ▸ | CYP17A1 | P05093 | 5/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.70 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.70 |
| ▸ | G6PD | P11413 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | SERPINA6 | P08185 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | GUSB | P08236 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | ESR1 | P03372 | 1/20 | 0.58 |
| ▸ | AR | P10275 | 1/20 | 0.58 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17776491 | 1.00 | SHBG (1.00) | SHBGCYP17A1ALDH1A1CYP2C9HIF1A | |
| SCHEMBL138937 | 1.00 | SHBG (1.00) | SHBGCYP17A1ALDH1A1CYP2C9HIF1A | |
| SCHEMBL142941 | 1.00 | SHBG (1.00) | SHBGCYP17A1ALDH1A1CYP2C9HIF1A | |
| SCHEMBL658688 | 1.00 | SHBG (1.00) | SHBGCYP17A1ALDH1A1CYP2C9HIF1A | |
| SCHEMBL735471 | 1.00 | SHBG (1.00) | SHBGCYP17A1ALDH1A1CYP2C9HIF1A | |
| SCHEMBL18373712 | 1.00 | SHBG (1.00) | SHBGCYP17A1ALDH1A1CYP2C9HIF1A | |
| SCHEMBL20457510 | 1.00 | SHBG (1.00) | SHBGCYP17A1ALDH1A1CYP2C9HIF1A | |
| SCHEMBL27633183 | 1.00 | SHBG (1.00) | SHBGCYP17A1ALDH1A1CYP2C9HIF1A | |
| Sulfuric Acid SCHEMBL1576876 | 0.96 | SHBG (0.91) | SHBGCYP17A1ALDH1A1CYP2C9HIF1A | |
| SCHEMBL31086698 | 0.92 | SHBG (0.85) | SHBGCYP17A1ALDH1A1CYP2C9HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102066346-A | Process for making substituted 2-amino-thiazolones | AMGEN INC | 2011-05-18 | — | — | CN | disclosed |