Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15906458 | 0.93 | BTK (0.72) | BTK | |
| SCHEMBL13893891 | 0.89 | BTK (0.61) | BTK | |
| SCHEMBL13893892 | 0.80 | BTK (0.52) | BTK | |
| SCHEMBL13894043 | 0.79 | BTK (0.49) | BTK | |
| SCHEMBL105806 | 0.79 | BTK (0.75) | BTK | |
| SCHEMBL13894015 | 0.77 | BTK (0.46) | BTK | |
| SCHEMBL1069382 | 0.77 | BTK (1.00) | BTK | |
| SCHEMBL13893945 | 0.77 | RAB9A (0.56) | BTK | |
| SCHEMBL13894045 | 0.76 | RAB9A (0.45) | BTK | |
| SCHEMBL12602968 | 0.76 | KDM4E (0.55) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009053269-A1 | NOVEL KINASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2009-04-30 | — | — | WO | disclosed |