Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAL | P20701 | 17/20 | 0.41 |
| ▸ | ITGB2 | P05107 | 16/20 | 0.41 |
| ▸ | ICAM1 | P05362 | 16/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13894278 | 0.92 | ITGB2 (0.42) | ITGALITGB2ICAM1 | |
| SCHEMBL13894065 | 0.87 | ITGAL (0.48) | ITGALITGB2ICAM1 | |
| SCHEMBL18868608 | 0.87 | ITGAL (0.45) | ITGALITGB2ICAM1 | |
| SCHEMBL18867977 | 0.86 | ITGAL (0.49) | ITGALITGB2ICAM1 | |
| SCHEMBL13894114 | 0.86 | ITGAL (0.48) | ITGALITGB2ICAM1 | |
| SCHEMBL18362338 | 0.86 | OPRM1 (0.38) | ITGALITGB2ICAM1OPRM1DRD2 | |
| SCHEMBL23176446 | 0.82 | ITGAL (0.48) | ITGALITGB2ICAM1 | |
| SCHEMBL18868508 | 0.81 | ITGAL (0.46) | ITGALITGB2ICAM1 | |
| SCHEMBL12169926 | 0.81 | ITGAL (0.65) | ITGALITGB2ICAM1 | |
| SCHEMBL18868588 | 0.81 | ITGAL (0.39) | ITGALITGB2ICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009054914-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF DIABETIC RETINOPATHY | SARCODE CORPORATION (US) | 2009-04-30 | — | — | WO | disclosed |