Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 18/20 | 0.42 |
| ▸ | ICAM1 | P05362 | 18/20 | 0.42 |
| ▸ | ITGAL | P20701 | 18/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13894134 | 0.92 | ITGAL (0.41) | ITGB2ICAM1ITGAL | |
| SCHEMBL18868566 | 0.80 | ITGB2 (0.55) | ITGB2ICAM1ITGAL | |
| SCHEMBL13894065 | 0.79 | ITGAL (0.48) | ITGB2ICAM1ITGAL | |
| SCHEMBL18868608 | 0.79 | ITGAL (0.45) | ITGB2ICAM1ITGAL | |
| SCHEMBL4755894 | 0.78 | ITGB2 (0.67) | ITGB2ICAM1ITGAL | |
| SCHEMBL13894114 | 0.78 | ITGAL (0.48) | ITGB2ICAM1ITGAL | |
| SCHEMBL18362338 | 0.78 | OPRM1 (0.38) | ITGB2ICAM1ITGAL | |
| SCHEMBL18868508 | 0.76 | ITGAL (0.46) | ITGB2ICAM1ITGAL | |
| SCHEMBL18868588 | 0.75 | ITGAL (0.39) | ITGB2ICAM1ITGAL | |
| SCHEMBL23176446 | 0.75 | ITGAL (0.48) | ITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009054914-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF DIABETIC RETINOPATHY | SARCODE CORPORATION (US) | 2009-04-30 | — | — | WO | disclosed |