Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | DRD4 | P21917 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | ITGAL | P20701 | 6/20 | 0.37 |
| ▸ | ITGB2 | P05107 | 5/20 | 0.37 |
| ▸ | ICAM1 | P05362 | 5/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | KYNU | Q16719 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18868608 | 0.86 | ITGAL (0.45) | ITGALITGB2ICAM1 | |
| SCHEMBL13894134 | 0.86 | ITGAL (0.41) | OPRM1DRD2DRD4DRD3ITGAL | |
| SCHEMBL13894114 | 0.85 | ITGAL (0.48) | ITGALITGB2ICAM1 | |
| SCHEMBL13894065 | 0.84 | ITGAL (0.48) | ITGALITGB2ICAM1 | |
| SCHEMBL18867977 | 0.84 | ITGAL (0.49) | ITGALITGB2ICAM1 | |
| SCHEMBL18867980 | 0.81 | DRD2 (0.37) | OPRM1DRD2DRD4DRD3ITGAL | |
| SCHEMBL23176446 | 0.80 | ITGAL (0.48) | ITGALITGB2ICAM1 | |
| SCHEMBL18868508 | 0.79 | ITGAL (0.46) | ITGALITGB2ICAM1 | |
| SCHEMBL18868588 | 0.79 | ITGAL (0.39) | ITGALITGB2ICAM1 | |
| SCHEMBL23176604 | 0.78 | ITGAL (0.46) | ITGALITGB2ICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2209371-B1 | COMPOSITIONS AND METHODS FOR TREATMENT OF DIABETIC RETINOPATHY | SARCODE BIOSCIENCE INC (US) | 2017-01-04 | — | — | EP | disclosed |