SCHEMBL13894367

SCHEMBL13894367

CC(C)(C)c1csc(C(C)(I)I)n1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR4 P51679 7/20 0.41
LMNA P02545 3/20 0.40
HTR1A P08908 1/20 0.39
HTR2A P28223 1/20 0.39
HTR7 P34969 1/20 0.39
ALDH1A1 P00352 4/20 0.38
ATAD2 Q6PL18 1/20 0.36
RAB9A P51151 7/20 0.35
NPC1 O15118 6/20 0.35
KMT2A Q03164 5/20 0.35
MEN1 O00255 4/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
MAPK1 P28482 2/20 0.35
POLB P06746 2/20 0.35
TAS1R3 Q7RTX0 1/20 0.35
TAS1R1 Q7RTX1 1/20 0.35
TAS1R2 Q8TE23 1/20 0.35
NPSR1 Q6W5P4 2/20 0.34
HPGD P15428 1/20 0.34
ALOX15 P16050 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20047420 0.87 CCR4 (0.41) CCR4LMNAHTR1AHTR2AHTR7
SCHEMBL2707018 0.84 CCR4 (0.44) CCR4LMNAHTR1AHTR2AHTR7
SCHEMBL17087991 0.78 CCR4 (0.41) CCR4LMNAHTR1AHTR2AHTR7
SCHEMBL24033639 0.75 HTR1A (0.40) CCR4LMNAHTR1AHTR2AHTR7
SCHEMBL20938007 0.75 HTR1A (0.40) CCR4LMNAHTR1AHTR2AHTR7
SCHEMBL21718743 0.73 CCR4 (0.43) CCR4LMNAHTR1AHTR2AHTR7
SCHEMBL18157876 0.72 CCR4 (0.46) CCR4LMNAHTR1AHTR2AHTR7
SCHEMBL3163858 0.70 CCR4 (0.44) CCR4LMNAHTR1AHTR2AHTR7
SCHEMBL77644 0.70 ALDH1A1 (0.49) CCR4LMNAHTR1AHTR2AHTR7
SCHEMBL12355728 0.70 LMNA (0.36) CCR4LMNAHTR1AHTR2AHTR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009055357-A1 DIAZEPANE COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2009-04-30 WO disclosed