Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR | Q13258 | 5/20 | 0.61 |
| ▸ | APP | P05067 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.43 |
| ▸ | ILK | Q13418 | 1/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TNIK | Q9UKE5 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9912187 | 0.77 | ALDH1A1 (0.44) | PTGDRALDH1A1SMN1; SMN2ILKNPC1 | |
| SCHEMBL4501379 | 0.76 | PTGDR (1.00) | PTGDRCNR2 | |
| SCHEMBL13894988 | 0.74 | CNR2 (0.44) | PTGDRALDH1A1SMN1; SMN2CNR2ILK | |
| SCHEMBL9912188 | 0.74 | PTGDR (0.64) | PTGDRALDH1A1SMN1; SMN2ILKNPC1 | |
| SCHEMBL9912208 | 0.73 | PTGDR (0.57) | PTGDRALDH1A1SMN1; SMN2MAPTADORA2A | |
| SCHEMBL13894999 | 0.71 | ALDH1A1 (0.47) | PTGDRALDH1A1SMN1; SMN2 | |
| SCHEMBL13895143 | 0.71 | ALDH1A1 (0.55) | PTGDRALDH1A1SMN1; SMN2RAB9ACYP1A2 | |
| SCHEMBL9912204 | 0.70 | PTGDR (0.56) | PTGDRALDH1A1SMN1; SMN2 | |
| SCHEMBL9912189 | 0.70 | BCHE (0.47) | PTGDRALDH1A1SMN1; SMN2 | |
| SCHEMBL13895056 | 0.70 | ALDH1A1 (0.44) | PTGDRALDH1A1SMN1; SMN2LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7517889-B2 | 2,6-substituted-4-monosubstitutedamino-pyrimidine as prostaglandin D2 receptor antagonists | AVENTIS PHARMACEUTICALS, INC. (US) | 2009-04-14 | — | — | US | disclosed |