Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 4/20 | 0.47 |
| ▸ | PTGDR | Q13258 | 9/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.43 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.41 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13894999 | 0.87 | ALDH1A1 (0.47) | PTGDRALDH1A1SMN1; SMN2PIK3CAPIK3CB | |
| SCHEMBL9912276 | 0.84 | PTGDR (0.63) | PTGDRALDH1A1SMN1; SMN2PIK3CAPIK3CB | |
| SCHEMBL4496062 | 0.83 | PTGDR (0.69) | PTGDR | |
| Hydrochloric Acid SCHEMBL4505180 | 0.82 | PTGDR (0.68) | PTGDR | |
| SCHEMBL9912204 | 0.82 | PTGDR (0.56) | PTGDRALDH1A1SMN1; SMN2PIK3CAPIK3CB | |
| SCHEMBL9912237 | 0.81 | PTGDR (0.52) | PTGDRALDH1A1SMN1; SMN2PIK3CAPIK3CB | |
| SCHEMBL9912281 | 0.78 | BRAF (0.61) | PTGDRALDH1A1SMN1; SMN2 | |
| SCHEMBL9912208 | 0.78 | PTGDR (0.57) | PTGDRALDH1A1SMN1; SMN2PIK3CAPIK3CB | |
| SCHEMBL9912203 | 0.77 | PTGDR (0.66) | PTGDRALDH1A1SMN1; SMN2PIK3CAPIK3CB | |
| SCHEMBL9912205 | 0.76 | PTGDR (0.52) | PTGDRALDH1A1SMN1; SMN2PIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8193183-B2 | 2,6-substituted-4-monosubstitutedamino-pyrimidine as prostaglandin D2 receptor antagonists | AVENTIS PHARMACEUTICALS INC. (US) | 2012-06-05 | — | — | US | disclosed |