Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR | Q13258 | 12/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.33 |
| ▸ | PRF1 | P14222 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.32 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.32 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.32 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.32 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13895140 | 0.89 | PTGDR (0.60) | PTGDRALDH1A1SMN1; SMN2ADORA3ADORA2A | |
| SCHEMBL4489823 | 0.78 | PTGDR (1.00) | PTGDR | |
| SCHEMBL9912187 | 0.76 | ALDH1A1 (0.44) | PTGDRALDH1A1SMN1; SMN2ADORA3ADORA2A | |
| SCHEMBL13895136 | 0.74 | PTGDR (0.61) | PTGDRALDH1A1SMN1; SMN2ADORA3ADORA2A | |
| SCHEMBL9912208 | 0.73 | PTGDR (0.57) | PTGDRALDH1A1SMN1; SMN2ADORA2APIK3CA | |
| SCHEMBL13895057 | 0.69 | PTGDR (0.62) | PTGDRALDH1A1SMN1; SMN2 | |
| SCHEMBL13895143 | 0.68 | ALDH1A1 (0.55) | PTGDRALDH1A1SMN1; SMN2RAB9APRKAB2 | |
| SCHEMBL13895056 | 0.68 | ALDH1A1 (0.44) | PTGDRALDH1A1SMN1; SMN2 | |
| SCHEMBL9912239 | 0.67 | PTGDR (0.63) | PTGDRALDH1A1SMN1; SMN2PIK3CAPIK3CB | |
| SCHEMBL13895060 | 0.67 | PTGDR (0.61) | PTGDRALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8193183-B2 | 2,6-substituted-4-monosubstitutedamino-pyrimidine as prostaglandin D2 receptor antagonists | AVENTIS PHARMACEUTICALS INC. (US) | 2012-06-05 | — | — | US | disclosed |