Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | SI | P14410 | 1/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | HMGCR | P04035 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16580102 | 0.82 | GAA (0.50) | GAAALOX15MGAMSIMGAM2 | |
| SCHEMBL20899760 | 0.82 | GAA (0.44) | GAAALOX15MGAMSIMGAM2 | |
| SCHEMBL17305098 | 0.82 | HMGCR (0.62) | GAAALOX15MGAMSIMGAM2 | |
| Hydrochloric Acid SCHEMBL18334584 | 0.80 | CYP1A2 (0.44) | GAAALOX15MGAMSIMGAM2 | |
| SCHEMBL8709491 | 0.80 | HMGCR (0.55) | ALOX15ALDH1A1CYP1A2HMGCRCHRM1 | |
| SCHEMBL11422035 | 0.79 | HMGCR (0.41) | GAAMGAMSIMGAM2HMGCR | |
| SCHEMBL10781352 | 0.78 | GAA (0.44) | GAAALOX15MGAMSIMGAM2 | |
| SCHEMBL7250728 | 0.78 | GAA (0.44) | GAAALOX15MGAMSIMGAM2 | |
| SCHEMBL7563037 | 0.76 | GAA (0.52) | GAAALOX15MGAMSIMGAM2 | |
| SCHEMBL927785 | 0.76 | GAA (0.52) | GAAALOX15MGAMSIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7521222-B2 | Farnesyl dibenzodiazepinone and processes for its production | THALLION PHARMACEUTICALS, INC. (CA) | 2009-04-21 | — | — | US | disclosed |
| US-20080199940-A1 | Farnesyl dibenzodiazepinone and processes for its production | ECOPIA BIOSCIENCES, INC. (CA) | 2008-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080199940-A1 | Farnesyl dibenzodiazepinone and processes for its production | FDPS, GGPS1, FNTB | GAA 3213/4885ALOX15 8/4885MGAM 2072/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.