Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 2/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.38 |
| ▸ | CDK2 | P24941 | 2/20 | 0.38 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.32 |
| ▸ | RGS12 | O14924 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.32 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29582678 | 0.84 | MAPK1 (0.50) | MAPK1CDK1CCNB1CCNA2CDK2 | |
| SCHEMBL7973683 | 0.83 | MAPK1 (0.56) | MAPK1CDK1CCNB1CCNA2CDK2 | |
| SCHEMBL7260723 | 0.79 | MAPK1 (0.49) | MAPK1CDK1CCNB1CCNA2CDK2 | |
| SCHEMBL12567829 | 0.78 | MAPK1 (0.46) | MAPK1CDK1CCNB1CCNA2CDK2 | |
| SCHEMBL19729179 | 0.77 | ALDH1A1 (0.47) | MAPK1LMNAALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL14241127 | 0.76 | MAPK1 (0.46) | MAPK1CDK1CCNB1CCNA2CDK2 | |
| SCHEMBL16480957 | 0.76 | MAPK1 (0.46) | MAPK1CDK1CCNB1CCNA2CDK2 | |
| SCHEMBL12286212 | 0.76 | MAPK1 (0.46) | MAPK1CDK1CCNB1CCNA2CDK2 | |
| SCHEMBL472171 | 0.76 | MAPK1 (0.46) | MAPK1CDK1CCNB1CCNA2CDK2 | |
| SCHEMBL1715525 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524977-B2 | Process for producing fluoroalkanesulfonamide derivatives | CENTRAL GLASS COMPANY, LIMITED (JP) | 2009-04-28 | — | — | US | disclosed |
| US-20080058538-A1 | Process for producing fluoroalkanesulfonamide derivatives | CENTRAL GLASS COMPANY, LIMITED (JP) | 2008-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080058538-A1 | Process for producing fluoroalkanesulfonamide derivatives | AFF1, AFF2, RER1 | MAPK1 963/4885CDK1 2665/4885CCNB1 1190/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.